Herpes simplex 200 mg 5 times daily or 4 hrly, doubled to 400 mg in severely immunocompromised. Suppression of Herpes simplex in adult 200 mg 4 hrly or 400 mg bid. Varicella & Herpes zoster 800 mg 5 times daily or 4 hrly, continued for 7 days.
May be taken with or without food: May be taken w/ meals to reduce GI discomfort.
Acute or chronic renal impairment.
Skin rash, GI effect, hematological & encephalopathic changes.