Zoladex

Zoladex

goserelin

Manufacturer:

AstraZeneca

Distributor:

DKSH
Concise Prescribing Info
Contents
Goserelin acetate
Indications/Uses
Prostate cancer suitable for hormonal manipulation, breast cancer in pre- & peri-menopausal women suitable for hormonal manipulation, endometriosis, endometrial thinning, uterine fibroids, assisted reproduction.
Dosage/Direction for Use
1 depot SC into the anterior abdominal wall, every 28 days. Endometrial thinning 2 inj to be given 4 wk apart. Surgery w/in 2 wk after 2nd inj. Uterine fibroids 3.6 mg w/ supplementary Fe for up to 3 mth before surgery.
Contraindications
Special Precautions
Men at risk of developing ureteric obstruction or spinal cord compression. Women w/ known metabolic bone disease. Polycystic ovarian syndrome.
Adverse Reactions
Hypersensitivity reactions (rare), arthralgia, nonspecific paraesthesias, rash, BP changes. Male Hot flushes, sweating, decrease in potency. Infrequently breast swelling & tenderness. Temporary increase in bone pain. Isolated cases of ureteric obstruction & spinal cord compression recorded. Female Hot flushes, sweating, change in libido, headache, mood changes including depression, vag dryness, change in breast size. Temporary increase in signs & symptoms. Rarely, patients w/ bony metastases have developed hypercalcaemia on initiation of therapy.
ATC Classification
L02AE03 - goserelin ; Belongs to the class of gonadotropin releasing hormone analogues. Used in endocrine therapy.
Presentation/Packing
Form
Zoladex SafeSystem depot inj 3.6 mg
Packing/Price
1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in