During shipment, to ensure that there is no loss of potency, the vaccine must be maintained at a temperature of 8°C (46°F) or colder, but not to exceed temperature lower than -50°C (-58°F). Use of dry ice may subject ZOSTAVAX to temperatures colder than -50°C (-58°F).
ZOSTAVAX should be stored refrigerated at a temperature of 2 to 8°C (36 to 46°F) or colder until it is reconstituted for injection (see Dosage & Administration). The diluent should be stored separately at a room temperature of (20 to 25°C, 68 to 77°F) or in the refrigerator at (2 to 8°C, 36 to 46°F).
Before reconstitution, protect from light.
Discard reconstituted vaccine if it is not used within 30 minutes.
Do not freeze reconstituted vaccine.