Many of the listed undesirable effects can be assigned to the anticholinergic and beta-adrenergic properties of BERODUAL. As with all inhalation therapy, BERODUAL may show symptoms of local irritation. Adverse drug reactions were identified from data obtained in clinical trials and pharmacovigilance during post approval use of the drug.
The most frequent side effects reported in clinical trials were cough, dry mouth, headache, tremor, pharyngitis, nausea, dizziness, dysphonia, tachycardia, palpitations, vomiting, blood pressure systolic increased and nervousness.
Immune system disorders: anaphylactic reaction, hypersensitivity.
Metabolism and nutritional disorders: hypokalaemia.
Psychiatric disorders: nervousness, agitation, mental disorder.
Nervous system disorders: headache, tremor, dizziness.
Eye disorders: glaucoma, intraocular pressure increased, accommodation disorder, mydriasis, vision blurred, eye pain, corneal oedema, conjunctival hyperaemia, halo vision.
Cardiac disorders: tachycardia, heart rate increased, palpitations, arrhythmia, atrial fibrillation, supraventricular tachycardia, myocardial ischaemia.
Respiratory, thoracic and mediastinal disorders: cough, pharyngitis, dysphonia, bronchospasm, throat irritation, pharyngeal oedema, laryngospasm, bronchospasm paradoxical, dry throat.
Gastrointestinal disorders: vomiting, nausea, dry mouth, stomatitis, glossitis, gastrointestinal motility disorder, diarrhoea, constipation, oedema mouth.
Skin and subcutaneous tissue disorders: urticaria, rash, pruritus, angioedema, hyperhidrosis.
Musculoskeletal and connective tissue disorders: muscular weakness, muscle spasms, myalgia.
Renal and urinary disorders: urinary retention.
Investigations: blood pressure systolic increased, blood pressure diastolic decreased.
Side effects which may occur during treatment should be reported to Doctors.