Adjunct in homocystinuria treatment
Adult: In patient w/ cystathionine beta-synthase (CBS) deficiency; 5,10-methylenetetrahydrofolate reductase deficiency; cobalamin co-factor metabolism defect: As powd for soln: Initially, 3 g bid, adjust dose according to plasma homocysteine concentration. Max: 20 g daily.
Child: <10 yr As powd for soln: 100 mg/kg daily in 2 divided doses, may increase gradually according to patient’s response up to 150 mg/kg daily. ≥10 yr Same as adult dose.
Child: <10 yr As powd for soln: 100 mg/kg daily in 2 divided doses, may increase gradually according to patient’s response up to 150 mg/kg daily. ≥10 yr Same as adult dose.