Betaloc Zok

Betaloc Zok Phản ứng phụ


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Adverse Reactions
Betaloc ZOK is well tolerated and adverse reactions have generally been mild and reversible. The following events have been reported as adverse events in clinical trials or reported from routine use, mostly with conventional Betaloc (metoprolol tartrate). In many cases, a relationship to treatment with Betaloc has not been established. The following definitions of frequencies are used: Very common (≥10%), common (1-9.9%), uncommon (0.1-0.9%), rare (0.01-0.09%) and very rare (<0.01%).
Cardiovascular System: Common: Bradycardia, postural disorders (very rare with syncope), cold hands and feet, palpitations. Uncommon: Transient deterioration of heart failure symptoms, cardiogenic shock in patients with acute MI, AV block I, oedema, precordial pain. Rare: Disturbances of cardiac conduction, cardiac arrhythmias. Very Rare: Gangrene in patients with preexisting severe peripheral circulatory disorders.
Central Nervous System: Very Common: Fatigue. Common: Dizziness, headache. Uncommon: Paraesthesia, muscle cramps.
Gastrointestinal: Common: Nausea, abdominal pain, diarrhoea, constipation. Uncommon: Vomiting. Rare: Dry mouth.
Haematologic: Very Rare: Thrombocytopenia.
Hepatic: Rare: Liver function test abnormalities. Very Rare: Hepatitis.
Musculoskeletal: Very Rare: Arthralgia.
Metabolism: Uncommon: Weight gain.
Psychiatric: Uncommon: Depression, impaired concentration, somnolence or insomnia, nightmares. Rare: Nervousness, anxiety, impotence/sexual dysfunction. Very Rare: Amnesia/memory impairment, confusion, hallucinations.
Respiratory: Common: Dyspnoea on exertion. Uncommon: Bronchospasm. Rare: Rhinitis.
Sensory Organs: Rare: Disturbances of vision, dry and/or irritated eyes, conjunctivitis. Very Rare: Tinnitus, taste disturbances.
Skin: Uncommon: Rash (in the form of urticaria psoriasiform and dystrophic skin lesions), increased sweating. Rare: Loss of hair. Very Rare: Photosensitivity reactions, aggravated psoriasis.
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