Enzymatic zonulysis for intracapsular lens extraction
Adult: Irrigate the posterior chamber with 1-2 mL of a 1:5000 diluted soln (150 N.F.u/mL). Then irrigate with at least 2 mL of the unused portion of the diluent 2-4 min after procedure.
Chỉ định và Liều dùng
Intraocular
Enzymatic zonulysis for intracapsular lens extraction Adult: Irrigate the posterior chamber with 1-2 mL of a 1:5000 diluted soln (150 N.F.u/mL). Then irrigate with at least 2 mL of the unused portion of the diluent 2-4 min after procedure.
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Chống chỉ định
Hypersensitivity. High vitreous pressure & a gaping incisional wound, congenital cataracts, patients < 20 yr due to probable lens-vitreous adhesion not responsive to α-chymotrypsin lysis.
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Tác dụng không mong muốn
IM: Occasionally, severe allergic reactions. Ophthalmological: Increased intraocular pressure, corneal oedema, striation & moderate uveitis.
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Tác dụng
Description: Chymotrypsin is a proteolytic enzyme obtained by the activation of chymotrypsinogen extracted from the pancreas of beef that has been used in ophthalmology for the dissection of the zonule of the lens, thus facilitating intracapsular cataract extraction & reducing trauma to the eye. It has also been given for its anti-inflammatory actions eg, in soft-tissue inflammation & oedema.
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Phân loại MIMS
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