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Chỉ định và Liều dùng
Oral
Hypertension Adult: 5-10 mg once daily, increase to 20 mg once daily if necessary.
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Chống chỉ định
Cardiogenic shock; recent MI or acute unstable angina; severe aortic stenosis.
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Thận trọng
Hypotension, poor cardiac reserve, heart failure. Sudden withdrawal may exacerbate angina. Discontinue in patients who experience ischemic pain following administration. Pregnancy, lactation.
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Tác dụng không mong muốn
Dizziness; flushing; headache; hypotension; peripheral oedema; tachycardia; palpitations; GI disturbances; increased micturition frequency; lethargy; eye pain; depression; ischaemic chest pain; cerebral or myocardial ischaemia; transient blindness; rashes; fever; abnormal liver function; gingival hyperplasia; myalgia; tremor; impotence.
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Tương tác
Other antihypertensives; aldesleukin; antipsychotics that cause hypotension; may modify insulin and glucose responses; quinidine; carbamazepine; phenytoin; rifampicin; cimetidine; erythromycin.
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Ảnh hưởng đến kết quả xét nghiệm
Falsely elevated spectrophotometric values of urinary vanillylmandelic acid.
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Tác dụng
Description: Cilnidipine is a dihydropyridine calcium-channel blocker. It inhibits cellular influx of calcium, thus causing vasodilatation. It has greater selectivity for vascular smooth muscle. It has little or no action at the SA or AV nodes and -ve inotropic activity is rarely seen at therapeutic doses.
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Phân loại MIMS
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Đăng xuất
