Pregnancy: 2 mg: Studies in animals show that drug has toxicity on embryo causing fetotoxicity and can cause congenital abnormalities. Therefore, glimepiride is contraindicated for pregnant women. People taking glimepiride were pregnant, immediately notify the physician to switch over to insulin therapy and insulin dose should be adjusted to keep blood glucose levels as normal.
Lactation: 2 mg: Glimepiride is excreted in breast milk. Therefore, glimepiride is contraindicated for breast-feeding women; insulin therapy should be used as an alternative mode. If glimepiride is required to use, they have to stop breastfeeding.
4 mg: Glimepiride should not be used during pregnancy and lactation.