Common: 1/100 ≤ADR <1/10, uncommon: 1/1000 ≤ADR <1/100, rare: 1/10,000 ≤ADR <1000, very rare: ADR <1/10,000.
Very common: Nausea, vomiting, diarrhoea (these gastrointestinal effects related to prostaglandin use are frequently reported).
Common: Cramping, light or moderate.
Skin and subcutaneous tissue:
Uncommon: Hypersensitivity: Skin rashes uncommon (0.2%).
Rare: Single cases of urticaria, erythroderma, erythema nodosum, toxic epidermal necrolysis have also been reported.
Very rare: Angioedema.
Infections and infestations:
Common: Infection following abortion. Suspected or confirmed infections (endometritis, pelvic inflammatory disease) have been reported in less than 5% of women.
Very rare: Cases of serious or fatal toxic shock caused by pathogens like Clostridium sordellii
endometritis or Escherichia coli
, presenting with or without fever or other obvious symptoms of infection, have been reported after medical abortion with the use of mifepristone.
Uncommon: Hypotension (0.25%).
Reproductive system and breast:
Very common: Uterine contractions or cramping (10 to 45%) in the hours following prostaglandin intake.
Common: Heavy bleeding occurs in about 5% of the cases.
Rare: Malaise, vagal symptoms (hot flushes, dizziness, chills), fever.