Instructions for Use/Handling: The vaccine should be re-suspended before use. When re-suspended, the vaccine will have a uniform hazy white appearance.
Upon storage, a fine white deposit
with a clear colourless layer above may be observed.
Re-suspension of the vaccine to obtain a uniform hazy white suspension: The vaccine can be re-suspended following the
steps as follows: Hold the syringe
upright in a closed hand.
the syringe by tipping it upside down and back again.
Repeat this action
vigorously for at least 15 seconds.
the vaccine again: If
the vaccine appears as a uniform hazy white suspension, it is ready to use – the appearance should not be clear.
the vaccine still does not appear as a uniform hazy white suspension - tip
upside down and back again for at least another 15 seconds - then inspect
The vaccine should be inspected visually for
any foreign particulate matter and/or abnormal physical appearance prior to
administration. In the event of either being observed, do not administer the
Any unused product or waste material should
be disposed of in accordance with local requirements.
Incompatibilities: Twinrix should not be mixed with other vaccines in the same syringe.