Vaccine, pneumococcal


Thông tin thuốc gốc
Chỉ định và Liều dùng
Intramuscular
Active immunisation against pneumococcal disease
Adult: As 13-valent conjugate vaccine: Primary immunisation: 0.5 mL as a single dose.
Child: As 10- or 13-valent conjugate vaccine: Primary immunisation: 6 weeks to 5 years 3 doses of 0.5 mL given at least 1 month apart. Booster dose given between 12-15 months of age or at least 6 months after the last dose. Alternatively, 2 doses of 0.5 mL given at 6 weeks of age, then 2nd dose given 2 months later. Booster dose given between 12-15 months of age or at least 6 months after the last dose. In unvaccinated infants and children: 7-11 months 2 doses of 0.5 mL give at least 1 month apart. 3rd dose at 2 years of age; 2-23 months 2 doses of 0.5 mL give at least 2 months apart; 2-17 years Same as adult dose.

Intramuscular, Subcutaneous
Active immunisation against pneumococcal disease
Adult: As 23-valent conjugate vaccine: Primary immunisation: 0.5 mL as a single dose via IM or SC inj. Revaccination may be considered for persons with increased risk.
Child: As 23-valent conjugate vaccine: ≥2 years Same as adult dose.
Chống chỉ định
Hypersensitivity.
Thận trọng
Patient with history of coagulation disorders (including thrombocytopenia), severe CV and pulmonary dysfunction, immunosuppression. Postpone vaccination in patients with moderate or severe acute febrile illness. Not indicated for treatment of pneumococcal infections. Renal and hepatic impairment. Children. Pregnancy and lactation.
Phản ứng phụ
Significant: Inj site reactions (e.g. pain, redness, bruising, swelling, induration); hypersensitivity reactions, fever, syncope, headache, rash.
General disorders and administration site conditions: Irritability, fatigue.
Metabolism and nutrition disorders: Decreased appetite.
Musculoskeletal and connective tissue disorders: Chills, myalgia, arthralgia.
Psychiatric disorders: Somnolence, insomnia.
IM/Parenteral/SC: C
Thông tin tư vấn bệnh nhân
This drug may cause syncope, if affected, do not drive or operate machinery.
MonitoringParameters
Monitor for hypersensitivity reactions 15 minutes after administration. Antibiotic prophylaxis should be continued after vaccination.
Tương tác
Increased risk of bleeding with anticoagulants. Decreased immune response with immunosuppressive therapies (e.g. high dose corticosteroids).
Tác dụng
Description: Pneumococcal vaccine, an inactive bacterial vaccine, contains purified capsular polysaccharides of pneumococcal serotypes 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F that promotes active immunisation against diseases caused by these S. pneumoniae serotypes.
Onset: Immunity: Approx 2-3 weeks.
Duration: At least 5 years.
Bảo quản
Store between 2-8°C. Do not freeze. Protect from light. Any unused portions should be disposed of in accordance with local requirements.
Phân loại ATC
J07AL - Pneumococcal vaccines ; Used for active immunizations.
References
Anon. Penumococcal Polysaccharide Vaccine (23-Valent). Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 10/07/2018.

Anon. Pneumococcal Conjugate Vaccine (10-Valent). Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 10/07/2018.

Anon. Pneumococcal Conjugate Vaccine (13-Valent). Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 10/07/2018.

Buckingham R (ed). Pneumococcal Vaccines. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 10/07/2018.

Joint Formulary Committee. Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed). British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 10/07/2018.

Pneumovax 23 Injection (Merck Sharp & Dohme Corp.). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 10/07/2018.

Thông báo miễn trừ trách nhiệm: Thông tin này được MIMS biên soạn một cách độc lập dựa trên thông tin của Vaccine, pneumococcal từ nhiều nguồn tài liệu tham khảo và được cung cấp chỉ cho mục đích tham khảo. Việc sử dụng điều trị và thông tin kê toa có thể khác nhau giữa các quốc gia. Vui lòng tham khảo thông tin sản phẩm trong MIMS để biết thông tin kê toa cụ thể đã qua phê duyệt ở quốc gia đó. Mặc dù đã rất nỗ lực để đảm bảo nội dung được chính xác nhưng MIMS sẽ không chịu trách nhiệm hoặc nghĩa vụ pháp lý cho bất kỳ yêu cầu bồi thường hay thiệt hại nào phát sinh do việc sử dụng hoặc sử dụng sai các thông tin ở đây, về nội dung thông tin hoặc về sự thiếu sót thông tin, hoặc về thông tin khác. © 2021 MIMS. Bản quyền thuộc về MIMS. Phát triển bởi MIMS.com
  • Pneumo 23
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in