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  • Fexofenadine - MIMS.com
Fexofenadine

Tác Động
Description: Fexofenadine is a non-sedating antihistamine and an active metabolite of terfenadine. It competes with histamine for H1-receptor on effector cells in the blood vessels, gastrointestinal tract and respiratory tract.
Onset: 2 hours.
Duration: 24 hours.
Pharmacokinetics:
Absorption: Rapidly absorbed from the gastrointestinal tract. Bioavailability: Approx 33%. Time to peak plasma concentration: 2 hours (orally disintegrating tab); approx 2.6 hours (conventional tab); approx 1 hour (susp).
Distribution: Plasma protein binding: 60-70% primarily to albumin and α1-acid glycoprotein.
Metabolism: Undergoes minimal metabolism in the liver (approx 5%) to methylester metabolite.
Excretion: Mainly via faeces (80%); via urine (12%, as unchanged drug). Elimination half-life: 14.4 hours.


Phân loại MIMS
Thuốc kháng histamin & kháng dị ứng Antihistamines & Antiallergics

Phân loại ATC
R06AX26 -  fexofenadine;  Belongs to the class of other antihistamines for systemic use.; 


Sản phẩm đang lưu hành
Telfor 60 [ DHG Pharma ]

Sản phẩm khác
AgimFast [ Agimexpharm ] Aleact [ Elder Pharmaceuticals ]
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Allerphast [ Mebiphar ] Allerstat [ Cadila Pharma ]
Altiva [ Ranbaxy Lab ] Amfendin [ Ampharco U.S.A ]
Axofen [ Aristopharma ] Bixofen [ BV Pharma ]
Cadifast [ Cagipharm ] Chemadin [ Chemfar Organics ]
Danapha-Telfadin [ Danapha ] Dofexo [ DOMESCO ]
Entefast [ Donaipharm ] Fanozo [ Mebiphar ]
Fegra 60/120/180 [ Pymepharco ] Felfor [ DHG Pharma ]
Fenafex [ Synmedic Lab ] Fenidofex [ OPV ]
Fexalar [ XL Laboratories ] Fexa-RB [ Raptakos-Brett ]
Fexet [ Getz Pharma ] Fexidine [ Strides Arcolab ]
Fexihist [ Ajanta Pharma ] Fexo/Torfast [ Torrent ]
FexodineFast [ SaVipharm ] Fexofast [ Boston Pharma ]
Fexon [ Axon Drugs Private ] Fexophar [ TV Pharm ]
Fexostad [ STADA-VN J.V ] Fexotamin [ Elegant ]
Finarine [ Highnoon Lab ] Fixdep [ Umedica ]
Genfix [ Genix Pharma ] Geofoxf [ M/S. Geofman ]
Glodas [ Glomed ] Hasalfast/Fexofenaderm [ Hasan-Dermapharm ]
Histaloc 120 [ Cagipharm ] Histofen [ Penta Labs ]
Imexofen [ Imexpharm ] Inflex [ Ind-Swift ]
Intas Allegix-120 [ Intas ] Kofixir [ XL Laboratories ]
Robfexo [ Cagipharm ] Telfadin [ Danapha ]
Telfast [ Sanofi-Aventis ] Telfor 120 [ DHG Pharma ]
Telfor 180 [ DHG Pharma ] Telgate [ NIC Pharma ]
Ternafast [ Mekophar ] Tilfur [ XL Laboratories ]
Tocimat [ Bidiphar ] Ultigra [ Medley ]
Xonadin [ Micro Labs ] Xonatrix Forte [ Davi Pharm ]

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