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Opioid systems influence ketamine’s antidepressant effect

Complex interactions between glutamatergic, opioidergic, and GABAergic systems modulate the antidepressant effects of ketamine on cerebral blood flow (CBF) in patients with major depressive disorder (MDD), suggests a recent study.

Opioid systems influence ketamine’s antidepressant effect

a day ago

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

a day ago by

Real-life use of letermovir in paediatric recipients of haematopoietic stem cell transplant (HSCT) is generally safe and prevents the development of cytomegalovirus (CMV) disease, as shown in a study presented at ESPID 2026.

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

a day ago

Lithium, antidepressant prevent relapse after ECT in patients with MDD

a day ago

A recent Delphi-based expert consensus has released guidelines on preventing relapse after a successful electroconvulsive therapy (ECT) for patients with major depressive disorder (MDD).

Lithium, antidepressant prevent relapse after ECT in patients with MDD

a day ago

Better CV health tied to lower severe COVID-19 risk in adults without CVD

a day ago by

In the C4R* consortium, better cardiovascular health (CVH)—as quantified by the AHA’s** Life’s Essential 8 (LE8)—is associated with a lower risk of severe COVID-19 (ie, hospitalization or death) in individuals without clinical cardiovascular disease (CVD).

Better CV health tied to lower severe COVID-19 risk in adults without CVD

a day ago

Malaria linked to poor growth outcomes in children

a day ago

Prenatal and early childhood exposure to malaria negatively affect growth outcomes in children, as suggested in a study.

Malaria linked to poor growth outcomes in children

a day ago

Novel petrelintide shows promise in obesity treatment

25 Jun 2026 by

Treatment with a once-weekly injectable petrelintide, a novel human amylin analogue, yields up to 10.7 percent weight loss through week 42 in adults with obesity or overweight, according to the phase II ZUPREME-1 trial presented at ADA 2026.

Novel petrelintide shows promise in obesity treatment

25 Jun 2026

Prenatal wildfire exposure in women with asthma adversely affects neonatal outcomes

24 Jun 2026

Exposure to wildfire smoke early in pregnancy in women with asthma carries an increased risk of adverse neonatal outcomes, as reported in a study.

Prenatal wildfire exposure in women with asthma adversely affects neonatal outcomes

24 Jun 2026

Age-based ivermectin dosing safe, efficacious in children with scabies infection

24 Jun 2026 by

In the treatment of scabies infection in children up to 2 years of age, age-based ivermectin dosing yields high response rates and is well-tolerated, according to the open-label phase 2 ITCHY 2 study.

Age-based ivermectin dosing safe, efficacious in children with scabies infection

24 Jun 2026

Nivolumab-relatlimab safer than ipilimumab-nivolumab in advanced cutaneous melanoma

24 Jun 2026

Treatment with nivolumab plus relatlimab results in a lower incidence of severe immune-related adverse events (irAEs), delayed onset of irAEs, and reduced rate of treatment discontinuation among patients with advanced cutaneous melanoma when compared with ipilimumab plus nivolumab, reports a study.

Nivolumab-relatlimab safer than ipilimumab-nivolumab in advanced cutaneous melanoma

24 Jun 2026

Severe bleeding after caesarean births reduced with prophylactic tranexamic acid

24 Jun 2026 by

Researchers in China have shown that administering tranexamic acid to women with placenta praevia resulted in a significant reduction in severe postpartum bleeding and at the same time there was no indication of a rise in serious adverse events. [BMJ 2026;393:e089636]

Severe bleeding after caesarean births reduced with prophylactic tranexamic acid

24 Jun 2026

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Opioid systems influence ketamine’s antidepressant effect

Opioid systems influence ketamine’s antidepressant effect

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

Lithium, antidepressant prevent relapse after ECT in patients with MDD

Lithium, antidepressant prevent relapse after ECT in patients with MDD

Better CV health tied to lower severe COVID-19 risk in adults without CVD

Better CV health tied to lower severe COVID-19 risk in adults without CVD

Malaria linked to poor growth outcomes in children

Malaria linked to poor growth outcomes in children

Novel petrelintide shows promise in obesity treatment

Novel petrelintide shows promise in obesity treatment

Prenatal wildfire exposure in women with asthma adversely affects neonatal outcomes

Prenatal wildfire exposure in women with asthma adversely affects neonatal outcomes

Age-based ivermectin dosing safe, efficacious in children with scabies infection

Age-based ivermectin dosing safe, efficacious in children with scabies infection

Nivolumab-relatlimab safer than ipilimumab-nivolumab in advanced cutaneous melanoma

Nivolumab-relatlimab safer than ipilimumab-nivolumab in advanced cutaneous melanoma

Severe bleeding after caesarean births reduced with prophylactic tranexamic acid

Severe bleeding after caesarean births reduced with prophylactic tranexamic acid