The Role of Bilastine in Treating Paediatric Patients with Allergic Rhinoconjunctivitis and Urticaria
24 Feb 2021;
Bilastine is a second-generation antihistamine
that has proven efficacy in treating urticaria and both seasonal and perennial
It has been shown to have a rapid onset of
action with fast effect as early as 30 minutes, and prolonged duration of
effect of more than 24 hours in adults.2–4
In paediatric patients, the therapeutic dose was
identified based on the results of a pharmacokinetic study demonstrating that
bilastine 10 mg once daily in children aged 2 to 11 years offers the same systemic
exposure as 20 mg once daily in adults.
Indications/Uses : Moderate to severe atopic dermatitis in adults & adolescents ≥12 yr who are candidates for systemic therapy. Add-on maintenance treatment for severe asthma w/ type 2 inflammation characterised by raised blood eosinophils &/or raised FeNO in adults & adolescents ≥12 yr who are inadequately controlled w/ high dose inhaled corticosteroid (ICS) plus another medicinal product for maintenance treatment.