Monotherapy or in combination w/ methotrexate (MTX) &/or DMARDs for moderate to severe active RA in adult patients. Monotherapy or in combination w/ MTX for active polyarticular juvenile idiopathic arthritis (pJIA) in patients from 2 yr. Active enthesitis-related arthritis in patients ≥6 yr. Adults w/ severe active ankylosing spondylitis (AS); axial spondyloarthritis. Moderate to severe chronic plaque psoriasis; active Crohn's disease & ulcerative colitis. Non-infectious intermediate, posterior & panuveitis. Severe chronic plaque psoriasis in childn & adolescents from 4 yr. Active moderate to severe hidradenitis suppurativa in adults from 12 yr. Moderate to severe active Crohn's disease in ped patient from 6 yr. Ped chronic non-infectious anterior uveitis in patients from 2 yr.