Tisagenlecleucel shows durable activity in R/R aggressive large B-cell lymphomas

The CD19-directed chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel has demonstrated durable activity and a manageable safety profile in adult patients with relapsed or refractory (R/R) aggressive large B-cell lymphomas (LBCLs) after long-term follow-up of the JULIET trial.

Higher BP variability tied to normal-tension glaucomatous optic neuropathy
Blood pressure (BP) variability is associated with normal-tension glaucomatous optic neuropathy (GON) via the hypoperfusion of the optic nerve, a recent study has found.
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