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Ibrutinib-bendamustine-rituximab combo promising for older patients with mantle-cell lymphoma 30 Jun 2022

A treatment combination comprising the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib plus bendamustine and rituximab, followed by rituximab maintenance therapy, improved progression-free survival (PFS) in older patients with untreated mantle-cell lymphoma, according to results of the SHINE* trial presented at ASCO 2022.

Poor glycaemic control tied to COVID-19 progression

30 Jun 2022

Persistent ALT elevation triples risk of future T2D among overweight, obese children

30 Jun 2022

Medication-assisted therapy tied to arrhythmia in patients with opioid use disorder

30 Jun 2022

Methotrexate proven safe, effective as first-line immunomodulator in paediatric Crohn's disease 30 Jun 2022
Use of methotrexate (MTX) appears safe and effective as first-line immunomodulator for maintenance therapy in children with Crohn’s disease (CD), suggests a study presented at the 54th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN 2022).