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Genetically predicted depression linked to multiple gastrointestinal disorders 31 May 2023
Genetic predisposition to major depressive disorder has the potential to increase the risk of gastrointestinal disorders such as gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), peptic ulcer disease, and nonalcoholic fatty liver disease (NAFLD), according to the results of a Mendelian randomization study.

First-line TB treatment: Faropenem rivals ethambutol in efficacy, with fewer side effects

31 May 2023

Children attending childcare more prone to respiratory virus infections

31 May 2023

How capable are SG obstetricians in performing operative vaginal delivery?

31 May 2023

Cytokine profile tied to treatment response in eczematous dermatitis

31 May 2023

Vaccination protects the young against COVID-19

31 May 2023

Cancer incidence uncommon among low-risk pancreatic cysts during extended surveillance

31 May 2023

Intermittent fasting tied to T2D remission

30 May 2023

Nitrate supplements may lower risk of diabetes complications, mortality in hyperglycaemic adults

30 May 2023

Cidofovir tied to quicker lesion clearance in patients with monkeypox

30 May 2023

Subgroup analysis CONFIRMs telipressin potential for treating HRS, alcoholic hepatitis

30 May 2023

Exploring Edoxaban in Patients with Atrial Fibrillation: Insights from Clinical Studies and Real-World Evidence 01 Jun 2023;
Atrial fibrillation (AF) is one of the most prevalent forms of cardiac arrhythmias, particularly among the ageing population. It is projected to affect about 8 and 17 million individuals in the United States and Europe in 2050, respectively. Although the prevalence of AF among Asians is relatively lower, the disease burden is high owing to the growing ageing population; approximately 72 million individuals are expected to receive an AF diagnosis in the next few decades. Stroke is a clinically important complication observed in patients with AF as its incidence rate is 4- to 5-fold higher than that in patients without AF. In particular, Asians have a higher incidence of AF-related risks of bleeding and stroke when compared with non-Asians. The annual risk of ischaemic stroke in Asian patients with AF was reported to be approximately 3%. As such, stroke prevention is an important aspect in the management of AF.