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Low-dose triple combination therapy on par with monotherapy in mild-to-moderate hypertension

26 May 2026

Treatment with a single-pill low-dose combination (LDC) of amlodipine, losartan, and chlorthalidone (ALC) results in similar reductions in blood pressure (BP) to those with standard-dose amlodipine monotherapy and greater BP decrease than losartan monotherapy over 8 weeks among patients with mild-to-moderate hypertension, reveals a study.

Low-dose triple combination therapy on par with monotherapy in mild-to-moderate hypertension

26 May 2026

One-day antibiotics suffice after adequate biliary drainage in acute cholangitis

26 May 2026 by

A 1-day course of antibiotics is noninferior to the standard 4–7-day regimen for achieving clinical cure in patients with acute cholangitis who have undergone adequate biliary drainage, according to the COBRA trial presented at ESCMID Global 2026.

One-day antibiotics suffice after adequate biliary drainage in acute cholangitis

26 May 2026

Are tests necessary for psoriasis patients treated with biologics?

25 May 2026

Many routine baseline screening and monitoring tests show no clear benefit to psoriasis patients prescribed biologic treatments, according to a study.

Are tests necessary for psoriasis patients treated with biologics?

25 May 2026

Aluminium adjuvanted vaccines do not cause autism, chronic diseases: study

25 May 2026 by

Treatment with aluminium adjuvanted vaccines does not appear to induce serious or long-term health outcomes, suggest the results of a systematic review. Local hypersensitivity reactions, such as persistent nodules and granulomas, are the most consistently recorded reactions.

Aluminium adjuvanted vaccines do not cause autism, chronic diseases: study

25 May 2026

Long-term dupilumab blocks relapse in moderate-to-severe atopic dermatitis

25 May 2026 by

The use of dupilumab significantly delays disease relapse in patients with moderate-to-severe atopic dermatitis (AD) while having an acceptable safety profile, reports a study.

Long-term dupilumab blocks relapse in moderate-to-severe atopic dermatitis

25 May 2026

Can low-dose atropine prevent myopia?

25 May 2026 by

In the ATOM*3 trial, atropine 0.01% did not prevent the onset of myopia in young children with premyopia (SE** +1.00 to −0.49 dioptres [D]) and low myopia (SE −0.50 to −1.50 D), but there was a trend towards less progression with atropine.

Can low-dose atropine prevent myopia?

25 May 2026

Real-world patients with perianal Crohn’s disease fare well with upadacitinib

25 May 2026

In patients with perianal Crohn’s disease (pCD) treated in routine clinical practice, the use of upadacitinib appears to have a beneficial effect on fistula outcomes, with a more pronounced effect seen for anti-TNF–naïve patients and those with shorter disease duration, according to a multicentre retrospective cohort study.

Real-world patients with perianal Crohn’s disease fare well with upadacitinib

25 May 2026

Low-volume PEG yields high-quality cleansing for bowel preparation in colonoscopy patients

24 May 2026

The use of a 1-litre (L) polyethylene glycol (PEG)-ascorbate in hospitalized adults undergoing elective colonoscopy results in higher rates of high-quality cleansing than a 2L PEG-ascorbate or 4L PEG, reports a study, noting comparable rates of adequate cleansing and high willingness to repeat.

Low-volume PEG yields high-quality cleansing for bowel preparation in colonoscopy patients

24 May 2026

Early antiviral treatment helps reduce risk of long COVID

23 May 2026 by

Individuals with acute COVID-19 who receive prompt antiviral treatment, such as ensitrelvir, nirmatrelvir, or molnupiravir, in the outpatient setting may be less likely to experience post–COVID-19 condition (PCC) compared with those who receive no treatment.

Early antiviral treatment helps reduce risk of long COVID

23 May 2026

Ketamine alleviates suicidal, depressive symptoms

23 May 2026

In patients with acute major depressive episodes (MDE), administering single or repeated intravenous ketamine infusions helps reduce suicidal and depressive symptoms, according to a meta-analysis.

Ketamine alleviates suicidal, depressive symptoms

23 May 2026

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Low-dose triple combination therapy on par with monotherapy in mild-to-moderate hypertension

Low-dose triple combination therapy on par with monotherapy in mild-to-moderate hypertension

One-day antibiotics suffice after adequate biliary drainage in acute cholangitis

One-day antibiotics suffice after adequate biliary drainage in acute cholangitis

Are tests necessary for psoriasis patients treated with biologics?

Are tests necessary for psoriasis patients treated with biologics?

Aluminium adjuvanted vaccines do not cause autism, chronic diseases: study

Aluminium adjuvanted vaccines do not cause autism, chronic diseases: study

Long-term dupilumab blocks relapse in moderate-to-severe atopic dermatitis

Long-term dupilumab blocks relapse in moderate-to-severe atopic dermatitis

Can low-dose atropine prevent myopia?

Can low-dose atropine prevent myopia?

Real-world patients with perianal Crohn’s disease fare well with upadacitinib

Real-world patients with perianal Crohn’s disease fare well with upadacitinib

Low-volume PEG yields high-quality cleansing for bowel preparation in colonoscopy patients

Low-volume PEG yields high-quality cleansing for bowel preparation in colonoscopy patients

Early antiviral treatment helps reduce risk of long COVID

Early antiviral treatment helps reduce risk of long COVID

Ketamine alleviates suicidal, depressive symptoms

Ketamine alleviates suicidal, depressive symptoms