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Pre-TURBT mitomycin-C improves RFS in NMIBC

26 Mar 2026 by

In the updated 5-year analysis of a randomized phase II trial, administering two doses of intravesical mitomycin-C (MMC) immediately before transurethral resection of bladder tumour (TURBT) improves recurrence-free survival (RFS) in individuals with non-muscle invasive bladder cancer (NMIBC).

Pre-TURBT mitomycin-C improves RFS in NMIBC

26 Mar 2026

Clozapine shows promise as second-line antipsychotic therapy

26 Mar 2026

In patients with first-episode psychosis who did not respond to initial antipsychotic treatment, the use of clozapine appears to improve clinical outcomes better than olanzapine and amisulpride, according to a study.

Clozapine shows promise as second-line antipsychotic therapy

26 Mar 2026

Patient education, collaboration allow safe deprescribing in older adults

25 Mar 2026

Deprescribing among older adults can be improved by overcoming systemic barriers, enhancing patient education, and implementing structured guidelines, suggests a study.

Patient education, collaboration allow safe deprescribing in older adults

25 Mar 2026

ThuFLEP noninferior to HoLEP in terms of functional outcomes in BPO

25 Mar 2026 by

Thulium fibre laser enucleation of the prostate (ThuFLEP) was noninferior to Holmium laser enucleation of the prostate (HoLEP) regarding functional outcomes over 24 months in patients with benign prostatic obstruction (BPO), according to a trial presented at EAU26.

ThuFLEP noninferior to HoLEP in terms of functional outcomes in BPO

25 Mar 2026

Enzalutamide improves outcomes in prostate cancer with hrBCR

24 Mar 2026 by

Treatment with enzalutamide monotherapy demonstrates numerically higher overall survival (OS) in prostate cancer patients with high-risk biochemical recurrence (hrBCR) when compared with leuprolide alone, but the difference is not statistically significant, as shown by the results of the EMBARK study.

Enzalutamide improves outcomes in prostate cancer with hrBCR

24 Mar 2026

Upadacitinib improves CD, UC in patients with prior tofacitinib failure

24 Mar 2026

Treatment with upadacitinib induces clinical remission and endoscopic improvement in most patients with severe, refractory Crohn’s disease (CD) or ulcerative colitis (UC) with prior tofacitinib failure, regardless of previous response to tofacitinib, a study has shown.

Upadacitinib improves CD, UC in patients with prior tofacitinib failure

24 Mar 2026

TXA POISEd for use in urologic surgery

24 Mar 2026 by

The POISE-3 trial supports the use of tranexamic acid (TXA) in patients undergoing urologic surgery at increased risk of bleeding.

TXA POISEd for use in urologic surgery

24 Mar 2026

Acid suppressant use tied to risk of ischaemic events in stroke patients on clopidogrel

24 Mar 2026

Acid suppressants such as potassium-competitive acid blockers (P-CABs) and proton pump inhibitors (PPIs), when used concomitantly with clopidogrel, carry an increased risk of ischaemic events in stroke patients, according to a retrospective cohort study.

Acid suppressant use tied to risk of ischaemic events in stroke patients on clopidogrel

24 Mar 2026

Less is more in relieving musculoskeletal pain in children

23 Mar 2026 by

In children with acute nonoperative musculoskeletal injury, treatment with ibuprofen alone appears adequate for relieving pain, with the addition of acetaminophen or hydromorphone yielding no additional analgesic effect, as shown in two No OUCH randomized clinical trials.

Less is more in relieving musculoskeletal pain in children

23 Mar 2026

Toxicology service a valuable resource in managing poisoning cases in SG: study

23 Mar 2026 by

Poisoned individuals form a substantial part of the patient population in Singapore, with prognoses that require early recognition and appropriate measures, according to a study.

Toxicology service a valuable resource in managing poisoning cases in SG: study

23 Mar 2026

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Pre-TURBT mitomycin-C improves RFS in NMIBC

Pre-TURBT mitomycin-C improves RFS in NMIBC

Clozapine shows promise as second-line antipsychotic therapy

Clozapine shows promise as second-line antipsychotic therapy

Patient education, collaboration allow safe deprescribing in older adults

Patient education, collaboration allow safe deprescribing in older adults

ThuFLEP noninferior to HoLEP in terms of functional outcomes in BPO

ThuFLEP noninferior to HoLEP in terms of functional outcomes in BPO

Enzalutamide improves outcomes in prostate cancer with hrBCR

Enzalutamide improves outcomes in prostate cancer with hrBCR

Upadacitinib improves CD, UC in patients with prior tofacitinib failure

Upadacitinib improves CD, UC in patients with prior tofacitinib failure

TXA POISEd for use in urologic surgery

TXA POISEd for use in urologic surgery

Acid suppressant use tied to risk of ischaemic events in stroke patients on clopidogrel

Acid suppressant use tied to risk of ischaemic events in stroke patients on clopidogrel

Less is more in relieving musculoskeletal pain in children

Less is more in relieving musculoskeletal pain in children

Toxicology service a valuable resource in managing poisoning cases in SG: study

Toxicology service a valuable resource in managing poisoning cases in SG: study