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The ratio of cardiac troponin (cTn) I and T helps differentiate acute necrotic from chronic/non-necrotic myocardial injury in clinical and experimental studies.

Use of cTnI/cTnT ratio improves AMI, myocardial injury discrimination

In the PREcoopERA window-of-opportunity trial, the selective estrogen receptor degrader (SERD) giredestrant shows robust anticancer activity, either alone or in combination with the luteinizing hormone-releasing hormone (LHRH) analogue triptorelin, in premenopausal women with ER+/HER2– operable invasive breast cancer.

Giredestrant ± LHRH analogue fares well in ER+/HER2– early breast cancer

18 May 2026 bởi

Giredestrant ± LHRH analogue fares well in ER+/HER2– early breast cancer

18 May 2026

Digoxin may mitigate worsening of rheumatic heart disease

Treatment with digoxin appears to reduce the risks of mortality and new-onset or worsening heart failure in patients with rheumatic heart disease (RHD), according to a study.

Digoxin may mitigate worsening of rheumatic heart disease

5-year PROFILE data: Top-down therapy able to modify longer-term course of CD

17 May 2026 bởi

A top-down approach of initiating treatment with infliximab plus immunomodulator upon diagnosis of Crohn’s disease (CD) reduces the risk of related abdominal surgery, as well as those of disease progression and hospitalization, as compared with the conventional step-up approach, according to long-term data from the PROFILE trial.

5-year PROFILE data: Top-down therapy able to modify longer-term course of CD

Myocardial infarction, injury up MACE risk

Patients with myocardial infarction (MI) and myocardial injury have a higher risk of developing future cardiovascular events, reveals a study.

Myocardial infarction, injury up MACE risk

Supervised home-based cardiorespiratory interval training reduces post-stroke fatigue

A home-based, supervised cardiorespiratory interval training program (HS-CITP) helps lessen fatigue among stroke survivors, as shown in a study.

Supervised home-based cardiorespiratory interval training reduces post-stroke fatigue

Folic acid supplementation may prevent adverse offspring outcomes in ASM-exposed pregnancies

In pregnant women exposed to antiseizure medications (ASMs), supplementation with folic acid helps lower the risk of adverse offspring outcomes, according to a study.

Folic acid supplementation may prevent adverse offspring outcomes in ASM-exposed pregnancies

GLP-1 RA prevents relapse, cuts weight in AUD patients with MetD

16 May 2026 bởi

Exposure to glucagon-like peptide-1 receptor agonists (GLP-1 RAs) demonstrates superiority over current FDA-approved pharmacotherapies for alcohol use disorder (AUD), reducing the risk of AUD after 1 year of therapy, reports a study presented at DDW 2026.

GLP-1 RA prevents relapse, cuts weight in AUD patients with MetD

Vunakizumab beneficial in axial spondyloarthritis

Treatment with vunakizumab appears to yield substantial improvements in signs and symptoms of radiographic axial spondyloarthritis (r-axSpA), as shown in a phase 2/3 trial.

Vunakizumab beneficial in axial spondyloarthritis