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Treating gout patients with urate-lowering therapy (ULT) to meet a serum urate level below 6 mg/dL within 12 months results in a reduced risk of major adverse cardiovascular events, as shown in a new user cohort study.

Treat-to-target ULT approach reduces cardiac risk in gout patients

PHP a promising alternative to endoscopic clip for post-EST bleeding

In patients with postendoscopic sphincterotomy (post-EST) bleeding, polysaccharide hemostatic powder (PHP) demonstrates noninferiority to endoscopic clip in the management of post-EST bleeding and is easier to use, reports a study.

PHP a promising alternative to endoscopic clip for post-EST bleeding

COMMIT: Triplet regimen extends PFS in select CRC patients

In the phase III COMMIT* trial, a combination of mFOLFOX6 (FFX), atezolizumab, and bevacizumab significantly improves progression-free survival (PFS) in patients with deficient mismatch repair or microsatellite instability-high metastatic colorectal cancer (dMMR/MSI-H mCRC).

COMMIT: Triplet regimen extends PFS in select CRC patients

04 Feb 2026

Obesity linked to poorer PFS in pembrolizumab-treated endometrial cancer

Among patients with endometrial cancer receiving treatment with pembrolizumab, those with obesity appear to have worse progression-free survival (PFS), according to a retrospective study.

Obesity linked to poorer PFS in pembrolizumab-treated endometrial cancer

177Lu-Dotatate boosts PFS in Asian patients with advanced GEP-NETs

Peptide receptor radionuclide therapy (PRRT) with lutetium-177 (¹⁷⁷Lu)-Dotatate significantly improved progression-free survival (PFS) among Asian patients with somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumours (GEP-NETs), according to the LUMINET-1 study presented at ESMO Asia 2025.

177Lu-Dotatate boosts PFS in Asian patients with advanced GEP-NETs

Investigational oral antibiotic noninferior to dual therapy for uncomplicated gonorrhoea

03 Feb 2026 bởi

In the treatment of uncomplicated urogenital gonorrhoea, a single dose of the novel oral antibiotic zoliflodacin shows similar efficacy and safety profile as the ceftriaxone plus azithromycin combination, as shown in a multinational phase III study.

Investigational oral antibiotic noninferior to dual therapy for uncomplicated gonorrhoea

Liver supplements popularity on the rise despite limited evidence

03 Feb 2026 bởi

The market for liver supplements is rapidly growing despite lacking scientific evidence to support their efficacy claims, reveals a study.

Liver supplements popularity on the rise despite limited evidence

In an updated analysis of the NATALEE* trial, the efficacy benefit of adjuvant ribociclib remains consistent even after the planned 3-year treatment duration for patients with HR+, ERBB2– early breast cancer (EBC).

NATALEE updates: Ribociclib benefit in HR+, ERBB– EBC sustained at 4 years

03 Feb 2026 bởi

NATALEE updates: Ribociclib benefit in HR+, ERBB– EBC sustained at 4 years

03 Feb 2026

Finerenone a viable option in primary aldosteronism treatment

The novel nonsteroidal mineralocorticoid receptor antagonist finerenone appears safe and efficacious in the treatment of primary aldosteronism, as shown in a study.

Finerenone a viable option in primary aldosteronism treatment