Syphilis - Primary References

Last updated: 01 April 2026
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  3. French P, Gomberg M, Janier M, et al. IUSTI: 2008 European guidelines on the management of syphilis. Int J STD AIDS. 2009 May;20(5):300-309. http://ijsa.rsmjournals.com. Accessed 28 May 2010. PMID: 19386965
  4. French P, Goh G, Goold P, et al. UK national guidelines on the management of syphilis 2008. Int J STD AIDS. 2008 Nov;19(11):729-740. http://www.bashh.org/guidelines. Accessed 29 May 2010. PMID: 18931264
  5. Mattei PL, Beachkofsky TM, Gilson RT, Wisco OJ. Syphilis: a reemerging infection. Am Fam Physician. 2012 Sep;86(5):433-440. PMID: 22963062
  6. Ferri FF. Syphilis. In: Alvero R, Borkan JM, Dobbs MR, et al, eds. Ferri's Clinical Advisor: Instant Diagnosis and Treatment. 1st ed. Philadelphia: Mosby Inc, an affiliate of Elsevier; 2010.
  7. MedWorm http://www.medworm.com/rss/index.php/Dermatology/12/ http://www.medworm.com/rss/medicalfeeds/specialities/Dermatology-News.xml
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  9. World Health Organization (WHO). Guidelines for the management of sexually transmitted infections. WHO. http://www.who.int. 2003. Accessed 28 May 2010.
  10. Canadian guideline on sexually transmitted infections: syphilis. Public Health Agency of Canada. http://www.phac-aspc.gc.ca. Accessed 28 May 2010.
  11. Management of patients who have genital ulcers. Centers for Disease Control and Prevention. http://www.cdc.gov. Accessed 28 May 2010.
  12. Management of genital ulcers & discharges (summary booklet). Ministry of Health Singapore. http://www.moh.gov.sg. May 2009. Accessed 31 May 2010.
  13. Syphilis. The New Zealand Sexual Health Society (NZSHS). http://www.nzshs.org. Accessed 28 May 2010.
  14. Syphilis-CDC fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/std/syphilis/STDFact-Syphilis-detailed.htm. Feb 2013. Accessed 16 Jul 2013.
  15. Lazaro N. Sexually transmitted infections in primary care 2013 (RCGP/BASHH). Royal College of General Practitioners. http://www.rcgp.org.uk. 2013. Accessed 30 May 2014.
  16. Kingston M, French P, Goh B, et al; Syphilis Guidelines Revision Group 2008, Clinical Effectiveness Group. UK national guidelines on the management of syphilis 2008. Int J STD AIDS. 19(11):729-740. doi: 10.1258/ijsa.2008.008279. PMID: 18931264
  17. Ministry of Health (MOH) Malaysia. National antibiotic guideline 2014, 2nd edition. Pharmaceutical Services Divisions, MOH Malaysia. http://www.pharmacy.gov.my. Dec 2014. Accessed 16 Jul 2015.
  18. World Health Organization (WHO). WHO guidelines for the treatment of Treponema pallidum (syphilis). WHO. http://www.who.int. 2016. Accessed 08 Sep 2016.
  19. Hook EW. Syphilis. Lancet. 2017 Apr 15;389(10078):1550-1557. http://dx.doi.org/10.1016/S0140-6736(16)32411-4. Accessed 03 May 2017
  20. Hicks CB, Clement M. Syphilis: epidemiology, pathophysiology, and clinical manifestations in patients with HIV. UpToDate. https://www.uptodate.com. 20 Dec 2023.
  21. Hicks CB, Clement M. Syphilis: screening and diagnostic testing. UpToDate. https://www.uptodate.com. 21 Aug 2024.
  22. Hicks CB, Clement M. Syphilis: treatment and monitoring. UpToDate. https://www.uptodate.com. 02 Aug 2024.
  23. Janier M, Unemo M, Dupin N, et al. 2020 European guideline on the management of syphilis. J Eur Acad Dermatol Venereol. 2021 May;35(3):574-588. doi: 10.1111/jdv.16946. PMID: 33094521
  24. World Health Organization (WHO). Updated recommendations for the treatment of Neisseria gonorrhoeae, Chlamydia trachomatis and Treponema pallidum (syphilis), and new recommendations on syphilis testing and partner services. WHO. https://www.who.int. 2024. Accessed 10 Mar 2026.