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One in five patients with chronic HBV infection achieves functional cure with bepirovirsen

The novel antisense oligonucleotide bepirovirsen has induced functional cure in one-fifth of patients with chronic hepatitis B virus (HBV) infection in the phase 3 B-Well 1 and B-Well 2 trials.

One in five patients with chronic HBV infection achieves functional cure with bepirovirsen

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Rheumatology patients must undergo screening for anxiety, depression, FM: study

1 hour ago

A significant proportion of rheumatology patients have been diagnosed with anxiety, depression, or fibromyalgia (FM), reveals a study, noting the importance of including screening for clinical decisions at all routine encounters.

Rheumatology patients must undergo screening for anxiety, depression, FM: study

1 hour ago

Heavy alcohol consumption raises CRC risk

2 hours ago by

Individuals with high alcohol consumption are at increased risk of colorectal cancer (CRC), reports a study, which shows that alcohol intake may trigger colorectal carcinogenesis through mechanisms operating across major molecular pathways for CRC.

Heavy alcohol consumption raises CRC risk

2 hours ago

$TNFi, IL-17i reduce risk of osteoporosis, but not hip fracture, in r-axSpA patients$

TNFi, IL-17i reduce risk of osteoporosis, but not hip fracture, in r-axSpA patients

3 hours ago

Patients with radiographic axial spondyloarthritis (r-axSpA) who have been exposed to tumour necrosis factor inhibitor (TNFi) and interleukin (IL)-17 inhibitor (IL-17i) appear to have a lower risk of osteoporosis, but not hip fracture, than biologic disease-modifying antirheumatic drug (bDMARD)-naïve individuals, a recent study has shown.

TNFi, IL-17i reduce risk of osteoporosis, but not hip fracture, in r-axSpA patients

3 hours ago

LNF-based regimens may alter trajectory of CHD treatment

4 hours ago by

Individuals with chronic hepatitis D (CHD) may benefit from lonafarnib boosted with ritonavir (LNF/RTV) alone or in combination with peg-interferon-alfa (PEG), findings from the phase III D-LIVR trial have shown.

LNF-based regimens may alter trajectory of CHD treatment

4 hours ago

$Lutikizumab shows promise in refractory hidradenitis suppurativa$

Lutikizumab shows promise in refractory hidradenitis suppurativa

8 hours ago

Treatment with lutikizumab appears to improve outcomes in patients with moderate-to-severe hidradenitis suppurativa (HS) who have not responded to anti-TNF therapy, according to a phase II trial.

Lutikizumab shows promise in refractory hidradenitis suppurativa

8 hours ago

Adverse reproductive factors plus unhealthy lifestyle tied to higher risk of cognitive decline

20 hours ago

In Chinese postmenopausal women, adverse reproductive factors combined with unhealthy lifestyle behaviours appear to be associated with increased likelihood of cognitive decline, as reported in a study.

Adverse reproductive factors plus unhealthy lifestyle tied to higher risk of cognitive decline

20 hours ago

Tezepelumab cuts oral corticosteroid use without compromising asthma control

a day ago by

Tezepelumab demonstrates steroid-sparing potential in patients with severe asthma, reducing maintenance oral corticosteroid use while maintaining asthma control, as shown in the phase III SUNRISE study.

Tezepelumab cuts oral corticosteroid use without compromising asthma control

a day ago

Early CKD screening in CAD patients must include eGFR, UACR: study

a day ago

A recent study has emphasized the importance of early screening for chronic kidney disease (CKD) among patients with coronary artery disease (CAD). Both estimated glomerular filtration rate (eGFR) and urinary albumin/creatinine ratio (UACR) must be included in the test to provide a complete diagnosis.

Early CKD screening in CAD patients must include eGFR, UACR: study

a day ago

Rapid response to obesity medications tied to greater weight loss

a day ago by

A post hoc analysis of the SURMOUNT-5 study reveals more tirzepatide-treated individuals with obesity achieving all body weight (BW) reduction thresholds than semaglutide-treated participants, with rapid responders showing a greater magnitude of weight loss.

Rapid response to obesity medications tied to greater weight loss

a day ago

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One in five patients with chronic HBV infection achieves functional cure with bepirovirsen

One in five patients with chronic HBV infection achieves functional cure with bepirovirsen

Rheumatology patients must undergo screening for anxiety, depression, FM: study

Rheumatology patients must undergo screening for anxiety, depression, FM: study

Heavy alcohol consumption raises CRC risk

Heavy alcohol consumption raises CRC risk

TNFi, IL-17i reduce risk of osteoporosis, but not hip fracture, in r-axSpA patients

TNFi, IL-17i reduce risk of osteoporosis, but not hip fracture, in r-axSpA patients

LNF-based regimens may alter trajectory of CHD treatment

LNF-based regimens may alter trajectory of CHD treatment

Lutikizumab shows promise in refractory hidradenitis suppurativa

Lutikizumab shows promise in refractory hidradenitis suppurativa

Adverse reproductive factors plus unhealthy lifestyle tied to higher risk of cognitive decline

Adverse reproductive factors plus unhealthy lifestyle tied to higher risk of cognitive decline

Tezepelumab cuts oral corticosteroid use without compromising asthma control

Tezepelumab cuts oral corticosteroid use without compromising asthma control

Early CKD screening in CAD patients must include eGFR, UACR: study

Early CKD screening in CAD patients must include eGFR, UACR: study

Rapid response to obesity medications tied to greater weight loss

Rapid response to obesity medications tied to greater weight loss