Hyperaldosteronism Disease Summary

Last updated: 28 June 2019

Overview

Hyperaldosteronism is a group of disorders in which aldosterone production is inappropriately high, relatively autonomous and non-suppressible by sodium loading.
Signs & symptoms are nonspecific; however, symptoms are caused by hypertension (eg headache), hypokalemia (eg polyuria, nocturia, muscle cramps and weakness, tetany, paralysis, etc) and metabolic alkalosis.
It must be noted that hypokalemia must first be corrected before performing any diagnostic study.
Patients with bilateral adrenal hyperplasia or those unsuitable for surgery is recommended to be treated medically by mineralocorticoid receptor antagonists.

For further information regarding the management of Hyperaldosteronism, please refer to Disease Algorithm for the Treatment Guideline.