Differential Diagnosis
Acute myelofibrosis is a rare form of acute myeloid leukemia characterized by a non-palpable spleen with rapid onset of severe bone marrow fibrosis with fever and pancytopenia, teardrop-shaped red blood cells (RBCs), and leukoerythroblastic blood features.
Other differentials include CML, essential
thrombocythemia, polycythemia
vera, myelodysplastic syndrome,
hairy cell leukemia, and multiple myeloma.