Cosentino G, Conrad AO, Uwaifo GI. Phentermine and topiramate for the management of obesity: a review. Drug Des Devel Ther. 2011 Apr;7:267-278. http://www.ncbi.nlm.nih.gov/. Accessed 31 Jul 2013. PMID: 23630412
Arterburn D, Hilton L, Li Z, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005 Apr;142(7):532-546. doi: 10.7326/0003-4819-142-7-200504050-00012. PMID: 15809465
Bray GA. Medical therapy for obesity--current status and future hopes. Med Clin North Am. 2007 Nov;91(6):1225-1253. doi: 10.1016/j.mcna.2007.06.013. PMID: 17964918
Lau DC, Douketis JD, Morrison KM, et al; Obesity Canada Clinical Practice Guidelines Expert Panel. 2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children [summary]. CMAJ. 2007 Apr;176(8):S1-S13. PMID: 17420481
James WP, Astrup A, Finer N. Effect of sibutramine on weight maintenance after weight loss: a randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance. Lancet. 2000 Dec;356(9248):2119-2125. doi: 10.1016/s0140-6736(00)03491-7. PMID: 11191537
Dickerson LM, Carek PJ. Pharmacotherapy for the obese patient. Prim Care. 2009 Jun;36(2):407-415. doi: 10.1016/j.pop.2009.01.004. PMID: 19501251
Mechanick JI, Garber AJ, Handelsman Y, et al. American Association of Clinical Endocrinologists' position statement on obesity and obesity medicine. Endocr Pract. 2012 Sep;18(5):642-648. doi: 10.4158/EP12160.PS. PMID: 23047927
Moyer VA; U.S. Preventive Services Task Force. Screening for and management of obesity in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2012 Sep;157(5):373-378. doi: 10.7326/0003-4819-157-5-201209040-00475. PMID: 22733087
Padwal R, Li S, Lau D. Long-term pharmacotherapy for obesity and overweight. Cochrane Database Syst Rev. 2004;2003(3):CD004094. doi: 10.1002/14651858.CD004094. PMID: 15266516
Shewmake RA, Huntington MK. Nutritional treatment of obesity. Prim Care. 2009 Jun;36(2):357-377. doi: 10.1016/j.pop.2009.01.010. PMID: 19501248
Torgerson JS, Hauptman J, Boldrin MN, et al. XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care. 2004 Jan;27(1):155-161. doi: 10.2337/diacare.27.1.155. PMID: 14693982
Snow V, Barry P, Fitterman N, et al; Clinical Efficacy Assessment Subcommittee of the American College of Physicians. Pharmacologic and surgical management of obesity in primary care: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2005 Apr;142(7):525-531. doi: 10.7326/0003-4819-142-7-200504050-00011. PMID: 15809464
WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004 Jan 10;363(9403):157-163. doi: 10.1016/S0140-6736(03)15268-3. PMID: 14726171
Tsigos C, Hainer V, Basdevant A, et al; Obesity Management Task Force of the European Association of the Study of Obesity. Management of obesity in adults: European clinical practice guidelines. Obes Facts. 2008;1(2):106-116. doi: 10.1159/000126822. PMID: 20054170
International Diabetes Federation (IDF). The IDF consensus worldwide definition of the metabolic syndrome. IDF. http://www.idf.org/. Apr 2005.
U.S. Food & Drug Administration (US FDA). Medication guide: Qsymia. US FDA. http://www.fda.gov/. 2012. Accessed 31 Jul 2013.
National Institute of Health, National Heart, Lung and Blood Institute (NHLBI), North American Association for the Study of Obesity. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. NHLBI. http://www.ncbi.nlm.gov/. 01 Oct 2000.
World Health Organization (WHO). Obesity and overweight. WHO. http://www.who.int. Accessed 11 Jun 2010.
Inoue S, Zimmet P, Caterson I, et al. The Asia-Pacific perspective: redefining obesity and its treatment. World Health Organization (WHO). https://iris.who.int/. Feb 2000.
National Institute for Health and Care Excellence (NICE). Obesity: guidance on the prevention, identification, assessment and management of overweight and obesity in adults and children. NICE. http://www.nice.org.uk/. Dec 2006. Accessed 11 Jun 2010.
Institute for Clinical Systems Improvement (ICSI). Prevention and management of obesity (mature adolescents and adults). ICSI. http://www.icsi.org. Apr 2011.
Apovian CM, Aronne LJ, Bessesen DH, et al. Pharmacological management of obesity: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2015 Feb;100(2):342-362. doi: 10.1210/jc.2014-3415. Accessed 6 Oct 2015. PMID: 25590212
Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task
Force on Practice Guidelines and the Obesity Society. Circulation. 2014 Jun;129(25)(Suppl 2):S102-S138. doi: 10.1161/01.cir.0000437739.71477.ee. Accessed 6 Oct 2015. PMID: 24222017
Gonzalez-Campoy JM, St Jeor ST, Castorino K, et al. Clinical practice guidelines for healthy eating for the prevention and treatment of metabolic and endocrine diseases in adults: cosponsored by the American Association of Clinical Endocrinologists/the American College of Endocrinology and the Obesity Society. Endocr Pract. 2013 Sep;19(Suppl 3):1-82. doi: 10.4158/EP13155.GL. Accessed 07 Apr 2014. PMID: 24129260
Guerrero AE, Gonzalez-Santos LE, Caole-Ang IV, et al. 2015 Updated clinical practice guidelines for the management of dyslipidemia in the Philippines. Philippine Society of Endocrinology, Diabetes and Metabolism. http://endo-society.org.ph. 2015. Accessed 03 Aug 2016.
Bray GA, Frühbeck G, Ryan DH, et al. Management of obesity. Lancet. 2016 May 7;387(10031):1947-1956. doi: 10.1016/S0140-6736(16)00271-3. PMID: 26868660
Garvey WT, Mechanick JI, Brett EM, et al; Reviewer of the AACE/ACE Obesity Clinical Practice Guidelines. American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity. Endocr Pract. 2016 Jul;22(Suppl 3):1-203. doi: 10.4158/EP161365.GL. Accessed 24 Aug 2017. PMID: 27219496
Gadde KM, Martin CK, Berthoud HR, et al. Obesity: pathophysiology and management. J Am Coll Cardiol. 2018 Jan 2;71(1):69-84. doi: 10.1016/j.jacc.2017.11.011. Accessed 16 Apr 2018. PMID: 29301630
Kasama K, Mui W, Lee WJ, et al. IFSO-APC consensus statements 2011. Obes Surg. 2012 May;22(5):677-684. doi: 10.1007/s11695-012-0610-7. PMID: 22367008
Durrer Schutz D, Busetto L, Dicker D, et al. European practical and patient-centred guidelines for adult obesity management in primary care. Obes Facts. 2019 Jan;12(1):40-66. doi: 10.1159/000496183. Accessed 19 Mar 2019. PMID: 30673677
Lim RB. Bariatric procedures for the management of severe obesity. UpToDate. https://www.uptodate.com. Sep 2018. Accessed 20 Mar 2019.
Perreault L. Obesity in adults: behavioral therapy. UpToDate. https://www.uptodate.com. Oct 2018. Accessed 20 Mar 2019.
Perreault L. Obesity in adults: drug therapy. UpToDate. https://www.uptodate.com. Feb 2019. Accessed 20 Mar 2019.
Ministry of Health (MOH) Singapore Health Promotion Board. Obesity clinical practice guidelines 1/2016. MOH Singapore. http://www.moh.gov.sg/. Jun 2016.
Wharton S, Lau DCW, Vallis M, et al. Obesity in adults: a clinical practice guideline. CMAJ. 2020 Aug 04;192(31):E875-891. doi: 10.1503/cmaj.191707. Accessed 19 Aug 2020. PMID: 32753461
Yumuk V, Tsigos C, Fried M, et al; Obesity Management Task Force of the European Association for the Study of Obesity. European guidelines for obesity management in adults. Obes Facts. 2015;8(6):402-424. doi: 10.1159/000442721. Accessed 06 Jan 2021. PMID: 26641646
Asokkumar R. Endoscopic sleeve gastroplasty: a non-surgical approach to obesity. SingHealth. https://www.singhealth.com.sg. 04 Nov 2020. Accessed 24 Feb 2021.
Bray GA, Kim KK, Wilding JPH, World Obesity Federation. Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation. Obes Rev. 2017 Jul;18(7):715-723. doi: 10.1111/obr.12551. Accessed 24 Feb 2021. PMID: 28489290
Coulter AA, Rebello CJ, Greenway FL. Centrally acting drugs for obesity: past, present, and future. Drugs. 2018 Jul;78(11):1113–1132. doi: 10.1007/s40265-018-0946-y. Accessed 24 Feb 2021. PMID: 30014268
Ohta M, Seki Y, Wong SK, et al. Bariatric/metabolic surgery in the Asia-Pacific region: APMBSS 2018 survey. Obes Surg. 2019 Feb;29(2):534-541. doi: 10.1007/s11695-018-3539-7. Accessed 24 Feb 2021. PMID: 30306499
Purcell K, Sumithran P, Prendergast LA, et al. The effect of rate of weight loss on long-term weight management: a randomised controlled trial. Lancet Diabetes Endocrinol. 2014 Dec;2(12):954-962. doi: 10.1016/S2213-8587(14)70200-1. Accessed 24 Feb 2021. PMID: 25459211
Rubino F, Nathan DM, Eckel RH, et al. Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations. Diabetes Care. 2016 Jun;39(6):861-877. doi: 10.2337/dc16-0236. Accessed 24 Feb 2021. PMID: 27222544
Veugen C, Teunissen EM, den Otter LAS, et al. Prediction of obstructive sleep apnea: comparative performance of three screening instruments on the apnea-hypopnea index and the oxygen desaturation index. Sleep Breath. 2020 Oct 24. doi: 10.1007/s11325-020-02219-6. Accessed 24 Feb 2021. PMID: 33098537
Centers for Disease Control and Prevention (CDC). Obesity, race/ethnicity, and COVID-19. CDC. https://www.cdc.gov. 22 Mar 2021. Accessed 13 Apr 2021.
World Obesity. Obesity and COVID-19 policy statement. World Obesity. https://www.worldobesity.org. Aug 2020. Accessed 13 Apr 2021.
Ryan DH. Semaglutide for obesity: four STEPs forward, but more to come. Lancet Diabetes Endocrinol. 2021 May;9(5):252-254. doi: 10.1016/S2213-8587(21)00081-4. Accessed 07 Jul 2021. PMID: 33864806
U.S. Food & Drug Administration (US FDA). Wegovy highlights of prescribing information. US FDA. https://www.accessdata.fda.gov. Jun 2021. Accessed 07 Jul 2021.
Shah P, Rathi P, Mandot A, et al. Study and comparison of metabolic profile of lean and obese subjects with non alcoholic fatty liver disease. J Assoc Physicians India. 2020 Aug;68(8):51-54. Accessed 20 Jul 2021. PMID: 32738842
Tak YJ, Lee SY. Long-term efficacy and safety of anti-obesity treatment: where do we stand?. Curr Obes Rep. 2021 Mar;10(1):14-30. doi: 10.1007/s13679-020-00422-w. Accessed 20 Jul 2021. PMID: 33410104
U.S. Food & Drug Administration (US FDA). Contrave highlights of prescribing information. US FDA. https://www.accessdata.fda.gov. Sep 2014. Accessed 20 Jul 2021.
Wharton S, Serodio KJ. Next generation of weight management medications: implications for diabetes and CVD risk. Curr Cardiol Rep. 2015 May;17(5):35. doi: 10.1007/s11886-015-0590-z. Accessed 20 Jul 2021. PMID: 25894803
Whyte MB, Velusamy S, Aylwin SJB. Disease severity and staging of obesity: a rational approach to patient selection. Curr Atheroscler Rep. 2014 Nov;16(11):456. doi: 10.1007/s11883-014-0456-7. Accessed 20 Jul 2021. PMID: 25278281
Yanovski SZ, Yanovski JA. Long-term drug treatment for obesity: a systematic and clinical review. JAMA. 2014 Jan 1;311(1):74-86. doi: 10.1001/jama.2013.281361. Accessed 20 Jul 2021. PMID: 24231879
Modi N, Priefer R. Effectiveness of mainstream diets. Obesity Medicine. 2020 Jun;18:100239. https://doi.org/10.1016/j.obmed.2020.100239. Accessed 28 Jul 2021
Vargas G, Azarbal J, Tota-Maharaj R. A comparative review of established diets for prevention of cardiovascular disease and newer dietary strategies. Curr Probl Cardiol. 2021 Mar;46(3):100582. doi: 10.1016/j.cpcardiol.2020.100582. Accessed 28 Jul 2021. PMID: 32389436
Visseren FLJ, Mach F, Smulders YM, et al; ESC National Cardiac Societies, ESC Scientific Document Group. 2021 ESC guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021 Sep 7;42(34):3227-3337. doi: 10.1093/eurheartj/ehab484. Accessed 15 Dec 2021. PMID: 34458905
Cornier MA. A review of current guidelines for the treatment of obesity. Am J Manag Care. 2022;28(Suppl 15):S288-S298. doi: 10.37765/ajmc.2022.89292. PMID: 36525676
Eisenberg D, Shikora SA, Aarts E, et al. 2022 American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO): Indications for metabolic and bariatric surgery. Surg Obes Relat Dis. 2022 Dec;18(12):1345-1356. doi: 10.1016/j.soard.2022.08.013. PMID: 36280539
Grunvald E, Shah R, Hernaez R, et al; AGA Clinical Guidelines Committee. AGA clinical practice guideline on pharmacological interventions for adults with obesity. Gastroenterology. 2022 Nov;163(5):1198-1225. doi: 10.1053/j.gastro.2022.08.045. PMID: 36273831
Bays HE, Bindlish S, Clayton TL. Obesity, diabetes mellitus, and cardiometabolic risk: an Obesity Medicine Association (OMA) clinical practice statement (CPS) 2023. ScienceDirect. https://reader.elsevier.com/. Jan 2023.
Ministry of Health Malaysia, Malaysia Endocrine & Metabolic Society, Malaysian Association for the Study of Obesity, Malaysian Dietitians' Association, Family Medicine Specialists Association of Malaysia. Clinical practice guidelines. Management of obesity. 2nd edition (2023). Academy of Medicine of Malaysia. https://www.acadmed.org.my/. May 2023. Accessed 25 Jun 2023.
Bindlish S, Ng J, Ghusn W, et al. Obesity, thrombosis, venous disease, lymphatic disease, and lipedema: an Obesity Medicine Association (OMA) clinical practice statement (CPS) 2023. Elsevier. https://doi.org/10.1016/j.obpill.2023.100092. 19 Oct 2023.
Clayton TL, Fitch A, Bays HE. Obesity and hypertension: Obesity Medicine Association (OMA) clinical practice statement (CPS) 2023. Elsevier. https://doi.org/10.1016/j.obpill.2023.100083. 07 Aug 2023.
Department of Health (DOH) Philippines. Philippine clinical practice guidelines for the screening and diagnosis of obesity in adults. DOH Philippines. https://doh.gov.ph. 05 Oct 2023.
Kim KK, Haam JH, Kim EM, et al; Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO). Evaluation and treatment of obesity and its comorbidities: 2022 update of clinical practice guidelines for obesity by the Korean Society for the Study of Obesity. J Obes Metab Syndr. 2023 Mar 30;32(1):1-24. doi: 10.7570/jomes23016. PMID: 36945077
Busetto L, Dicker D, Fruhbeck G, et al. A new framework for the diagnosis, staging and management of obesity in adults. Nat Med. 2024 Jul 5. doi: 10.1038/s41591-024-03095-3. Accessed 10 Jul 2024. PMID: 38969880
Bays HE, Kirkpatrick C, Maki KC, et al. Obesity, dyslipidemia, and cardiovascular disease: a joint expert review from the Obesity Medicine Association and the National Lipid Association 2024. Obes Pillars. 2024 Mar 12;10:100108. doi: 10.1016/j.obpill.2024.100108. PMID: 38706496
American Diabetes Association. Standards of care in diabetes - 2025. Diabetes Care. 2025 Jan;48(Suppl 1):S1-S352. https://diabetesjournals.org/. Accessed 19 Dec 2024
Kittleson MM, Benjamin EJ, Blumer V, et al. 2025 ACC scientific statement on the management of obesity in adults with heart failure: a report of the American College of Cardiology. J Am Coll Cardiol. 2025 Jun 10;S0735-1097(25):06481-2. doi: 10.1016/j.jacc.2025.05.008. Accessed 07 Jul 2025. PMID: 40512113
Qin W, Yang J, Deng C, et al. Efficacy and safety of semaglutide 2.4 mg for weight loss in overweight or obese adults without diabetes: an updated systematic review and meta-analysis including the 2-year STEP 5 trial. Diabetes Obes Metab. 2024 Mar;26(3):911-923. doi: 10.1111/dom.15386. PMID: 38016699
Gilbert O, Gulati M, Gluckman TJ, et al. 2025 Concise clinical guidance: an ACC expert consensus statement on medical weight management for optimization of cardiovascular health: a report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2025 Aug 19;86(7):536-555. doi: 10.1016/j.jacc.2025.05.024. Accessed 11 Aug 2025. PMID: 40539956
Pedersen SD, Manjoo P, Dash S, et al. Canadian adult obesity clinical practice guideline: pharmacotherapy for obesity management in adults: 2025 clinical practice guideline update. CMAJ. 2025 Aug 10;197(27):E797-E809. doi: 10.1503/cmaj.250502. Accessed 26 Nov 2025. PMID: 40789597
American Diabetes Association. Standards of care in diabetes - 2026. Diabetes Care. 2026 Jan;49(Suppl S1):S377. https://professional.diabetes.org/standards-of-care. Accessed 12 Jan 2026
Tchang BG, Aras M, Kumar RB, et al. Pharmacologic treatment of overweight and obesity in adults. In: Feingold KR, Adler RA, Ahmed SF, et al, eds. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2024. https://www.ncbi.nlm.nih.gov.
Kansakar U, Jankauskas SS, Pande S, et al. Orforglipron: a comprehensive review of an oral small-molecule GLP-1 receptor agonist for obesity and type 2 diabetes. Int J Mol Sci. 2026 Jan;30(27)(Suppl 3). doi: 10.3390/ijms27031409. PMID: 41683830
