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Onasemnogene abeparvovec commonly linked to hepatotoxicity 27 Feb 2021
Hepatotoxicity is common after treatment with onasemnogene abeparvovec for spinal muscular atrophy, a recent study has found. Clinicians should anticipate and be ready to manage such adverse events, and be aware of any potential underlying conditions that could aggravate them.

COVID-19 vaccines vs new variants: Are we protected?

27 Feb 2021

Neck size useful in screening for metabolic syndrome

27 Feb 2021

Immune checkpoint inhibitors deliver comparable effectiveness in advanced urothelial carcinoma

27 Feb 2021

Pancreatic enzymes supplementation leads to symptomatic recovery in sorafenib-treated HCC

27 Feb 2021

Risk for thrombotic events higher after respiratory infections needing hospitalization

27 Feb 2021

Metformin shields diabetics against tuberculosis

27 Feb 2021

Severe/critical COVID-19 may up perinatal risk

26 Feb 2021

Decongestants do not aggravate stroke, MI risk

26 Feb 2021

Adjuvant S-1 + docetaxel yields survival benefit for stage III gastric cancer patients following resection

26 Feb 2021

Drug eluting vs covered metal stents: which is more beneficial in malignant biliary strictures?

26 Feb 2021

A Guide on Primary Immunodeficiency Disease and Allergies 05 Feb 2021;

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Optimizing metastatic hormone-sensitive prostate cancer treatment in advanced prostate cancer

Assoc Prof. Darren Poon, Assoc Prof. Edmund Chiong, 14 Jan 2021

ALL treatment: Current settings, future goals

Roshini Claire Anthony, 08 Jan 2021

Spotlight on multidrug-resistant gram-negative infections: New developments for an old problem

Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021

Trezilent

Contents : Alpelisib

Indications/Uses : In combination w/ fulvestrant for postmenopausal women & men w/ hormone-receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer following progression on or after endocrine-based regimen.

Vizimpro

Contents : Dacomitinib

Indications/Uses : 1st-line treatment of patients w/ metastatic non-small cell lung cancer (NSCLC) w/ epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations.

Adacel

Contents : Per 0.5 mL Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, pertactin 3 mcg, fimbriae types 2 & 3 5 mcg

Indications/Uses : Active booster immunization for prevention of tetanus, diphtheria & pertussis (whooping cough) in persons ≥4 yr. Passive protection against pertussis in early infancy following maternal immunization during pregnancy. Concomitant w/ inactivated poliomyelitis vaccine as alternative for 5th dose of tetanus, diphtheria & acellular pertussis vaccine (DTaP) in childn 4-6 yr.

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