Cap Adult 60 mg (1 cap) to be taken once daily to tds. Retard capAdult 90 mg once daily depending on the disorder & severity. If necessary, daily dosage can be taken bd & may be increased up to 180 mg.
Should be taken with food: Take during meals. Swallow whole.
Unresolved dyshaematopoiesis & hypersensitivity to acemetacin or indomethacin, NSAIDs/analgesics. Patients who suffer from asthma, hay fever, swollen nasal mucosa or chronic respiratory disease. Patients w/ gastric & duodenal ulcers. Severe heart failure. Treatment of peri-op pain in the setting of CABG surgery. History of GI bleeding or perforation, related to previous NSAIDs therapy; active or history of recurrent peptic ulcer/haemorrhage. Pregnancy & lactation.
Patients w/ history of gastric or duodenal ulcers; GI symptoms; impaired liver or kidney function; HTN; heart failure. Platelet aggregation may be affected in patients w/ increased haemorrhagic tendency. Risk of serious CV thrombotic events, MI, stroke; serious GI adverse events; renal effects; renal toxicity in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. Not recommended in patients w/ advanced renal disease. May impair ability to drive or operate machinery. Childn. Elderly.