Amican

Amican

candesartan

Manufacturer:

Myungmoon

Distributor:

Yu Chun
/
SB Pharma
Concise Prescribing Info
Contents
Candesartan cilexetil
Indications/Uses
Essential HTN in adults. Heart failure & impaired LVEF in adults as add-on therapy to ACE inhibitors or when ACE inhibitors are not tolerated.
Dosage/Direction for Use
HTN Adult Initial or maintenance dose 8 mg once daily. May be increased to 16 mg once daily & up to max 32 mg once daily. Elderly No initial dose adjustment. Patients w/ intravascular vol depletion Initially 4 mg. Patient w/ renal impairment Initially 4 mg. Patient w/ mild to moderate hepatic impairment Initially 4 mg once daily. Heart failure Adult Initially 4 mg once daily. May be increased up to max 32 mg once daily by doubling the dose at 2 wk intervals. Elderly No initial dose adjustment. Patients w/ intravascular vol depletion No initial dose adjustment. Patient w/ renal impairment No initial dose adjustment. Patient w/ mild to moderate hepatic impairment No initial dose adjustment.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Severe hepatic impairment &/or cholestatis. Pregnancy (2nd & 3rd trimesters).
Special Precautions
Concomitant therapy w/ ACE inhibitors in heart failure. Haemodialysis. Renal artery stenosis. Recent kidney transplantation. Hypotension. Anaesth & surgery. Aortic & mitral valve stenosis (obstructive hypertrophic cardiomyopathy). Primary hyperaldosteronism. Hyperkalaemia. Renal impairment. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Pregnancy (1st trimester). Lactation.
Drug Interactions
Increased K levels w/ K-sparing diuretics, K supplements, K-containing salt substitute, heparin. Reversible increases in lithium conc & toxicity. Attenuated antihypertensive effect, increased risk of worsening renal function & increased serum K w/ NSAIDs.
ATC Classification
C09CA06 - candesartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Amican tab 8 mg
Packing/Price
3 × 10's
Form
Amican tab 16 mg
Packing/Price
3 × 10's
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in