Amoksiklav

Amoksiklav

amoxicillin + clavulanic acid

Manufacturer:

Sandoz

Distributor:

Zuellig
/
Four Star
Concise Prescribing Info
Contents
Per 375 mg FC tab Amoxicillin trihydrate 250 mg, clavulanate K 125 mg. Per 1,000 mg FC tab Amoxicillin trihydrate 875 mg, clavulanate K 125 mg. Per 156.25 mg/5 mL powd for oral susp Amoxicillin trihydrate 125 mg, clavulanate K 31.25 mg
Indications/Uses
Upper & lower resp tract infections, acute & chronic otitis media, UTI, gynecological infections, gonorrhea (caused by β-lactamase-producing gonococcus), infection from bites of animals or man; skin & soft tissue infections, bone & joint infections, cholecystitis, chancroid, odontogenic infections. Treatment of mixed infections due to gm -ve & gm +ve microorganisms & anaerobes eg, chronic sinusitis & otitis, cerebral, mammary or peritonsillar abscess, aspiration pneumonia, peritonitis, cholangitis, post-op intra-abdominal complications, mixed abdominal infections.
Dosage/Direction for Use
375 mg FC tab Adult & childn weighing >40 kg Usual dose: 1 tab every 8 hr. 1,000 mg FC tab Adult & childn weighing >40 kg Usual dose: 1 tab bd. Higher dose: 1 tab tds. 156.25 mg/5 mL powd for oral susp Childn <40 kg Usual dose: 20 mg/5 mg to 60 mg/15 mg for each kg of body wt per day, given in 3 divided doses.
Administration
May be taken with or without food: May be taken w/ meals for better absorption & to reduce GI discomfort.
Contraindications
Hypersensitivity to amoxicillin, clavulanic acid, penicillins, or any other antibiotics. Infectious mononucleosis, lymphatic leukemia. History of liver problems or jaundice when taking antibiotic.
Special Precautions
Patient w/ history of allergic reactions; oliguria; severe renal or hepatic impairment. May cause or exacerbate allergic reactions, convulsions & inflammation of the large intestine. False +ve glucose reaction in urine using Benedict's reagent. +ve results in Coombs' test. Pregnancy. Do not administer to a nursing mother.
Adverse Reactions
GI disturbances eg, nausea, vomiting, diarrhea. Skin reactions, elevated hepatic enzymes. Candidiasis.
Drug Interactions
Increased MTX toxicity. Increased incidence of exanthema w/ allopurinol. Physically & chemically incompatible w/ aminoglycosides. Potential interaction w/ probenecid or anticoagulants (eg, warfarin).
MIMS Class
Penicillins
ATC Classification
J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
Presentation/Packing
Form
Amoksiklav FC tab 1,000 mg
Packing/Price
70's
Form
Amoksiklav FC tab 375 mg
Packing/Price
70's
Form
Amoksiklav 156.25 mg/5 mL oral susp
Packing/Price
1's
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