Use w/ caution in patients w/ renal, pulmonary or CV disease; patients prone to nausea & vomiting; patients taking vasoactive medicinal products eg, antihypertensives; patients w/ pre-existing postural hypotension; patients at risk for Torsades de pointes arrhythmia. Risk of local SC effects; haemolytic anaemia & thrombocytopenia; somnolence & episodes of sudden sleep onset; development of impulse control disorders; dopamine dysregulation syndrome. Neuropsychiatric disturbances may be exacerbated. Concomitant use w/ other medicinal products especially those w/ narrow therapeutic range. Minor or moderate influence on the ability to drive & use machines. Elderly &/or debilitated patients. Pre-filled syringe:
Contains Na metabisulphite. Pre-filled pen:
Contains Na bisulphite.