1,600 mg daily as a single dose. Dose exceeding 1,600 mg must be taken separately (as a 2nd dose). Hypercalcemia
2,400-3,200 mg daily, may be reduced to 1,600 mg daily if applicable. Osteolysis
Initially 1,600 mg daily, may be increased to a max of 3,200 mg daily if necessary. Renal insufficiency CrCl 50-80 mL/min
1,600 mg daily, 30-50 mL/min
1,200 mg daily, <30 mL/min
800 mg daily.