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Brot

Brot

metformin

Manufacturer:

Medochemie

Distributor:

DCH Auriga - Universal
Concise Prescribing Info
Contents
Metformin HCl
Indications/Uses
Type 2 DM (NIDDM) in overwt patients when diet & exercise alone have not been enough to control blood glucose levels.
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Dosage/Direction for Use
Adult Initially 500 or 850 mg bd-tds. Max dose: 3,000 mg/day taken as 3 divided doses. Childn & adolescents >10 yr Initially 500 or 850 mg once daily. Max dose: 2,000 mg/day taken as 2 or 3 divided doses. Renal impairment w/ GFR 60-89 mL/min Total max dose: 3,000 mg/day in 2-3 divided doses, GFR 45-59 mL/min Total max dose: 2,000 mg/day in 2-3 divided doses, GFR 30-44 mL/min Total max dose: 1,000 mg/day in 2-3 divided doses.
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Overdosage
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Administration
Should be taken with food.
Contraindications
Hypersensitivity. Uncontrolled diabetes w/ severe hyperglycaemia, nausea, vomiting, diarrhoea, rapid wt loss, lactic acidosis or ketoacidosis. Dehydration. Excessive alcohol intake. Acute heart failure or recent heart attack, severe circulatory problems (eg, shock) or breathing difficulties. Severe infections. Liver problems. Severely reduced kidney function.
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Warnings
For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Brot detailed prescribing information
Special Precautions
Risk of lactic acidosis. Discontinue use in case of conditions that may be associated w/ dehydration; symptoms of lactic acidosis; major surgery. Intravascular administration of iodinated contrast agents. Risk of hypoglycaemia w/ other antidiabetics (eg, sulphonylureas, insulin, meglitinides). Renal impairment. Pregnancy & lactation.
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Adverse Reactions
Digestive problems (eg, nausea, vomiting, diarrhoea, abdominal pain & loss of appetite). Changes in taste.
Drug Interactions
Diuretics; NSAIDs & COX-2 inhibitors (eg, ibuprofen & celecoxib); ACE inhibitors & AIIA; β2 agonists (eg, salbutamol or terbutaline); corticosteroids; medicines that may change the amount of Brot in the blood, especially if w/ reduced kidney function (eg, verapamil, rifampicin, cimetidine, dolutegravir, ranolazine, trimethoprime, vandetanib, isavuconazole, crizotinib, olaparib); other antidiabetics. Increased risk of lactic acidosis w/ excessive alcohol intake.
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Storage
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Description
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Action
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MIMS Class
Antidiabetic Agents
ATC Classification
A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.
Presentation/Packing
Form
Brot FC tab 500 mg
Packing/Price
50 × 10's
Form
Brot FC tab 850 mg
Packing/Price
50 × 10's
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