Do not inj intravascularly, SC or intradermally. No available data on interchangeability w/ other COVID-19 vaccines; individuals who received 1st dose should receive 2nd dose to complete the vaccination course. Close observation for at least 15 min following vaccination; do not give 2nd dose if anaphylaxis to 1st dose occurred. Postpone vaccination in individuals suffering from acute severe febrile illness or acute infection. Bleeding or bruising may occur following IM administration; caution in individuals receiving anticoagulant therapy or those w/ thrombocytopenia or any coagulation disorder (eg, haemophilia). Duration of protection is still being determined by ongoing clinical trials. May not protect all vaccine recipients; individuals may not be fully protected until 7 days after 2nd dose. Immunocompromised individuals. Pregnancy & lactation. Childn & adolescents <16 yr.