Cotiasar

Cotiasar

losartan + hydrochlorothiazide

Manufacturer:

Tecnimede

Distributor:

Firma Welfare Instrument
/
T-BOMA
Concise Prescribing Info
Contents
Losartan K 50 mg, hydrochlorothiazide 12.5 mg
Indications/Uses
Management of HTN.
Dosage/Direction for Use
1 tab once daily, may increase to 2 tab once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to losartan K, hydrochlorothiazide & other sulfonamide-derived drugs; anuria. Pregnancy.
Special Precautions
Hepatic or severe renal impairment. Hypotension & electrolyte/fluid imbalance. Adjust dose antidiabetics & insulin if taken concomitantly. Discontinue prior to parathyroid function tests. Patient at risk of hyperuricemia &/or gout, at risk of SLE exacerbation/activation. Lactation. Childn.
Adverse Reactions
Dizziness, asthenia/fatigue, vertigo.
Drug Interactions
Reduced lithium excretion. Reduced effect w/ NSAIDs. Reduced levels of losartan w/ rifampicin & fluconazole. Increased serum K levels w/ K-sparing diuretics, K supplements or salt substitutes containing K. Potentiation of orthostatic hypotension w/ alcohol, barbiturates, narcotics. Additive effect w/ other antihypertensives. Impaired hydrochlorothiazide absorption w/ cholestyramine, colestipol resins. Intensify hypokalemia w/ corticosteroids, ACTH or glycyrrhizin. Decreased response to pressor amines. Increased responsiveness to muscle relaxant w/ nondepolarizing skeletal muscle relaxants.
ATC Classification
C09DA01 - losartan and diuretics ; Belongs to the class of angiotensin II receptor blockers (ARBs) in combination with diuretics. Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Cotiasar tab 50 mg/12.5 mg
Packing/Price
6 × 10's
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