Maxidex

Maxidex

dexamethasone

Manufacturer:

Novartis

Distributor:

Zuellig
/
Firma Chun Cheong
Concise Prescribing Info
Contents
Dexamethasone
Indications/Uses
Treatment of corticosteroid responsive inflammatory conditions of the palpebral & bulbar conjunctiva, cornea & anterior segment of the globe eg, allergic conjunctivitis, keratitis as a consequence of acne rosacea, superficial punctate keratitis, iritis, cyclitis, corneal injuries from chemical products, radiation, burns or foreign bodies, when the inherent hazard of corticosteroid use is accepted to obtain a perceptible diminution in oedema & inflammation.
Dosage/Direction for Use
Ophth oint Apply small amount of oint (1-1.5 cm) into the conjunctival sac up 1-4 times daily. When favourable response is observed, gradually reduce to once daily for several days. Ophth susp 1-2 drops in the conjunctival sac. In severe inflammation, instillations may be made hrly & subsequently at longer intervals until treatment discontinuation. In less severe inflammation, administer 4-6 times daily.
Contraindications
Hypersensitivity. Herpetic keratitis (dendritic keratitis), vaccinia, varicella & other viral diseases of the cornea & the conjunctiva; tuberculous lesions; untreated bacterial infections of the eye; fungal diseases of the eye structures. Should not be used after uncomplicated removal of a corneal foreign body or w/ infections or injuries limited to the superficial corneal epithelium.
Special Precautions
To be prescribed & renewed only after exam by slitlamp biomicroscopy & fluorescein test. Not for treatment of Sjogren's keratoconjunctivitis. Increased risk of ocular complications & systemic side effects w/ excessive &/or prolonged use. Ocular HTN &/or glaucoma w/ damage to the optic nerve, defects in visual acuity & field of vision, & posterior subcapsular cataract formation upon prolonged use. If used for ≥10 days, routinely monitor IOP. May mask infection or exacerbate an existing infection. Consider possibility of persistent fungal infections of the cornea after prolonged use. Use w/ great caution in the treatment of herpes simplex. Perforations in diseases causing thinning of the cornea or sclera. Flare-up of the inflammatory condition may occur w/ sudden interruption of highly dosed corticosteroids. Do not instill while wearing contact lenses. May affect ability to drive or use machines. Pregnancy & lactation. Ophth susp Contains benzalkonium Cl.
Adverse Reactions
Increased IOP. Rarely, eye irritation, visual acuity reduced, subcapsular cataract, glaucoma, visual field defects, hypersensitivity, eye infection.
Drug Interactions
Additional elevation of IOP w/ pupil-dilating eye drops (atropine & other anticholinergics). If supplementary eye prep are to be used, wait about 15 min between 2 applications.
MIMS Class
Eye Corticosteroids
ATC Classification
S01BA01 - dexamethasone ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.
Presentation/Packing
Form
Maxidex ophth susp 0.1 %
Packing/Price
5 mL x 1's
Form
Maxidex ophthalmic ointment 0.1 %
Packing/Price
(tube) 3.5 g x 1's
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