Blood disorder eg, thrombocytopenia or clotting disorders. Febrile convulsions not related to previous vaccination. Fever ≥40°C; collapse or shock-like state w/ hypotonic-hyporesponsive episode; persistent, inconsolable crying lasting ≥3 hr occurring w/in 48 hr of vaccination; convulsion w/ or w/o fever occurring w/in 3 days of vaccination. Allergic reactions. Guillain-Barre syndrome & brachial neuritis. Oedematous reactions of the lower limbs following vaccination containing H. influenzae
type b. Patients on immunosuppressive treatment or w/ immune deficiency.