Renvela

Renvela

sevelamer

Manufacturer:

Sanofi

Distributor:

DCH Auriga - Healthcare
Concise Prescribing Info
Contents
Sevelamer carbonate
Indications/Uses
Control of hyperphosphataemia in adult patients on haemodialysis or peritoneal dialysis, or w/ chronic kidney disease not on dialysis w/ serum P ≥1.78 mmol/L. Use in multiple therapeutic approach to control the development of renal bone disease.
Dosage/Direction for Use
Patients w/ serum P levels >2.42 mmol/L Total daily dose: 4.8 g to be taken over 3 meals/day; 1.78-2.42 mmol/L Total daily dose: 2.4 g to be taken over 3 meals/day.
Administration
Should be taken with food: Swallow whole, do not chew/crush/divide.
Contraindications
Hypersensitivity; hypophosphataemia, bowel obstruction.
Special Precautions
Patient w/ chronic kidney disease not on dialysis w/ serum P level <1.78 mmol/L. Dysphagia; swallowing disorders; severe GI motility disorders; active inflammatory bowel disease, major GIT surgery. Intestinal obstruction & ileus/subileus. Peritonitis. Assess regularly serum vit A, D, E & K status. Possible folate deficiency. Metabolic acidosis. Hypocalcaemia/hypercalcaemia. Hypothyroidsim. Not indicated for control of hyperparathyroidism. Long-term chronic treatment. Pregnancy & lactation. Childn <18 yr.
Adverse Reactions
Nausea, vomiting, upper abdominal pain, constipation. Diarrhoea, dyspepsia, flatulence, abdominal pain.
Drug Interactions
Decreased bioavailability of ciprofloxacin. Reduced levels of ciclosporin, mycophenolate mofetil & tacrolimus. Very rare cases of hypothyroidism in combination w/ levothyroxine. Very rare cases of increased phosphate levels w/ proton pump inhibitors.
MIMS Class
Antidotes & Detoxifying Agents
ATC Classification
V03AE02 - sevelamer ; Belongs to the class of drugs used in the treatment of hyperkalemia and hyperphosphatemia.
Presentation/Packing
Form
Renvela FC tab 800 mg
Packing/Price
180's
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