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Vesicare衛喜康

Vesicare

solifenacin

Manufacturer:

Astellas

Distributor:

Firma Chun Cheong
/
DKSH
Concise Prescribing Info
Contents
Solifenacin succinate
Indications/Uses
Symptomatic treatment of overactive bladder, including strong, sudden urge to urinate w/o prior warning & frequent urinating or wetting.
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Dosage/Direction for Use
5-10 mg daily.
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Overdosage
View Vesicare overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Swallow whole w/ liqd, do not chew/crush.
Contraindications
Hypersensitivity. Patients suffering from urinary retention; severe stomach or bowel condition (including toxic megacolon); myasthenia gravis; glaucoma. Patients undergoing kidney dialysis. Patients w/ severe liver disease; severe kidney or moderate liver disease & concomitantly treated w/ medicines that may decrease Vesicare elimination.
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Special Precautions
Discontinue treatment if anaphylactic reactions &/or angioedema w/ airway obstruction occur. Patients suffering from bladder obstruction or difficulty in passing urine (eg, thin urine flow); constipation; at risk of digestive system slowing down (stomach & bowel movements); severe kidney disease; moderate liver disease; stomach tear (hiatus hernia) or heartburn; autonomic neuropathy. Patients w/ risk factors for QT prolongation eg, pre-existing abnormal ECG & high K levels. Do not use in patients w/ rare hereditary problem of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May affect ability to drive or operate machinery. Pregnancy. Do not use if breast-feeding. Do not use in childn or adolescents <18 yr.
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Adverse Reactions
Dry mouth. Blurred vision; constipation, nausea, indigestion, stomach discomfort.
Drug Interactions
Enhanced side effects w/ other anticholinergics. Reduced efficacy w/ cholinergics. Reduced efficacy of metoclopramide & cisapride. Decreased metabolic rate w/ ketoconazole, ritonavir, nelfinavir, itraconazole, verapamil & diltiazem. Increased metabolic rate w/ rifampicin, phenytoin & carbamazepine. Medicines that exacerbate or cause gullet inflammation eg, bisphosphonates.
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Storage
View Vesicare storage conditions for details to ensure optimal shelf-life.
Description
View Vesicare description for details of the chemical structure and excipients (inactive components).
Action
View Vesicare mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Drugs for Bladder & Prostate Disorders
ATC Classification
G04BD08 - solifenacin ; Belongs to the class of urinary antispasmodics.
Presentation/Packing
Form
Vesicare FC tab 10 mg
Packing/Price
30's
Form
Vesicare FC tab 5 mg
Packing/Price
30's
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