May be taken with or without food: Swallow whole w/ liqd, do not chew/crush.
Patient undergoing kidney dialysis. Severe liver disease. Intolerance to some sugars. Patient suffering from urinary retention; severe stomach or bowel condition; myasthenia gravis; high pressure in eyes w/ gradual loss of eyesight (glaucoma).
Patient suffering from blockage of bladder, digestive system obstruction; reflux disease (including heartburn) or hiatus hernia; autonomic neuropathy; angioedema; preexisting abnormal ECG; high potassium. Concomitant w/ aspirin, ibuprofen or other NSAIDs; biphosphonates; medicines that may decrease the removal of Vesicare from the body. May affect ability to drive or operate machinery. Pregnancy & lactation.