Initially 20 mg/day as a single evening dose. Adjust at 4-wk intervals to a max of 80 mg/day. Hyperlipidemia
Initially 10-20 mg daily as a single evening dose. Homozygous familial hypercholesterolemia
40 mg/day in the evening or 80 mg/day in 3 divided doses of 20 mg, 20 mg & an evening dose of 40 mg, Concomitant therapy
In patients taking cyclosporine, fibrates or niacin concomitantly, max: 10 mg/day.