Adenosine


Generic Medicine Info
Contraindications
2nd or 3rd degree AV block, sick sinus syndrome (except in patient w/ functional pacemaker), long QT syndrome, severe hypotension, unstable angina, decompensated heart failure, asthma, COPD.
Special Precautions
Patient w/ QT prolongation, emphysema, bronchitis, autonomic dysfunction, pericarditis, pericardial effusion, left main coronary stenosis, stenotic valvular heart disease, stenotic carotid artery disease (w/ cerebrovascular insufficiency), uncorrected hypovolemia, left to right shunt, recent MI or heart transplant, severe heart failure, minor conduction defects (e.g. 1st degree AV block, bundle branch block), atrial fibrillation/flutter, history of convulsion/seizure. Pregnancy and lactation. Monitoring Parameters Monitor ECG, BP, and heart rate. Continuously monitor cardiac and haemodynamic states during infusion.
Adverse Reactions
Nausea, light-headedness, flushing, headache, angina-like chest pain, apprehension, dyspnoea, bronchospasm; bradycardia, heart block; tachy- and bradyarrhythmia, AF, MI; abdominal, throat, neck, and jaw discomfort. Rarely, hypotension, reflex tachycardia, severe bradycardia.
Potentially Fatal: Cardiac and resp arrest, asystole. Rarely, ventricular fibrillation.
Drug Interactions
Increased effect w/ dipyridamole. Reduced effect w/ xanthines (e.g. aminophylline, theophylline). May produce higher degree of heart block w/ carbamazepine. May cause ventricular fibrillation w/ digoxin or digoxin and verapamil combination.
CIMS Class
ATC Classification
C01EB10 - adenosine ; Belongs to the class of other cardiac preparations.
Disclaimer: This information is independently developed by CIMS based on adenosine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in