Concise Prescribing Info
Listed in Dosage.
Dosage/Direction for Use
Adult: Parenteral Severe pain; Chronic pain; Trigeminal neuralgia As 100% dehydrated alcohol: 0.2 mL up to a max of 10 mL, given via inj into the nerve root or ganglion ideally located via radiographic or fluoroscopic imaging prior to admin. IV Antidote for methanol or ethylene glycol ingestion As 100% dehydrated alcohol: Loading: 600-800 mg/kg given via infusion over 30 mins thru central venous catheter. Maintenance: 80-83 mg/kg/hr (non-drinker); 120-138 mg/kg/hr (average adult); 184-196 mg/kg/hr (drinker). As 10% ethanol: Loading: 7.5 mL/kg given via infusion over 30 min thru central venous catheter. Maintenance: 0.83 mL/kg/hr (non-drinker); 1.38 mL/kg/hr (average adult); 1.96 mL/kg/hr (drinker). Topical Antiseptic and disinfectant As 70% soln: Clean then apply a small amount on the affected area 1-3 times daily.
Seizure, diabetic coma. Concomitant use w/ opioid preparations.
Special Precautions
Patient w/ DM, gout, shock. Patient who underwent recent cranial surgery. Hepatic and renal impairment. Childn. Pregnancy and lactation. Patient Counselling This drug may cause dizziness, if affected, do not drive or operate machinery. Monitoring Parameters Monitor blood ethanol levels 1-2 hrly until steady state (100-150 mg/L) is reached, then 2-4 hrly thereafter. Monitor for signs and symptoms of CNS and resp depression. Monitor for methanol/ethylene glycol blood levels, blood glucose, arterial pH, blood gases, heart rate, and BP.
Adverse Reactions
Nervous: Headache, dizziness, tremor, lethargy, amnesia, stupor, coma, loss of judgement, emotional lability, slurred speech, ataxia, dysarthia. CV: Cardiomyopathy, hypotension, HTN, CV collapse. GI: Nausea, vomiting. Resp: Resp depression. Endocrine: Hypoglycaemia. Musculoskeletal: Muscle incoordination. Ophthalmologic: Visual impairment, nystagmus. Others: Hypothermia.
ROUTE(S) : IV / Parenteral: C
ROUTE(S) : PO: D X if used in large amounts or for prolonged periods.
Drug Interactions
May cause unpleasant disulfiram-like reactions w/ chlorpropramide, metronidazole and some cephalosporins. May cause hypoglycaemia w/ sulphonylurea and insulin. May cause orthostatic hypotension w/ vasodilators (e.g. ACE inhibitors, adrenergic neuron blockers, β-blockers).
Disclaimer: This information is independently developed by CIMS based on alcohol from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in