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Indications/Uses
Listed in Dosage.
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Dosage/Direction for Use
Adult: PO Susceptible infections 400-800 mg 2-3 times/day. Uncomplicated gonorrhoea W/ probenecid: 1.6 g as a single dose.
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Administration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
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Contraindications
Infectious mononucleosis, lymphatic leukemia, HIV infection; hypersensitivity to penicillins.
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Special Precautions
Very high doses in poor renal function (risk of neurotoxicity) or heart failure. Avoid contact, skin sensitisation may occur. Monitor serum potassium concentration, renal and haematological status. Spirochete infections particularly syphilis; suprainfection with penicillin-resistant organisms with prolonged use; avoid intrathecal route. Discontinue in case of skin rash.
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Adverse Reactions
Hypersensitivity reactions including uticaria; fever; joint pains; rashes; angioedema; serum sickness-like reactions; haemolytic anaemia; interstitial nephritis; neutropenia; thrombocytopenia; CNS toxicity including convulsions; diarrhoea; antibiotic-associated colitis. Nausea; vomiting; pseudomembranous colitis.
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Drug Interactions
Probenecid prolongs T1/2 of bacampicillin. Bacteriostatic drugs e.g. chloramphenicol, tetracyclines; other antibacterials; anticoagulants.
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CIMS Class
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ATC Classification
J01CA06 - bacampicillin ; Belongs to the class of penicillins with extended spectrum. Used in the systemic treatment of infections.
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