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Contraindications
Coma; CNS depression; pheochromocytoma; bone marrow suppression. Pregnancy and lactation.
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Special Precautions
Hepatic or renal impairment; history of jaundice; CV disease; angle-closure glaucoma; diabetes mellitus; hyperthyroidism; Parkinson's disease; epilepsy, depression, myasthenia gravis; prostatic hypertrophy; severe resp disease; blood dyscrasias. May precipitate coma, affect driving; elderly.
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Adverse Reactions
Alter temp regulation; neuroleptic malignant syndrome; CNS effects (extrapyramidal effects); GI disturbances; nasal congestion; antimuscurinic symptoms; CV symptoms, endocrine effects; blood dyscrasias; photosensitization, contact sensitization and rashes; jaundice; corneal and lens opacities; purplish pigmentation of skin, cornea, conjunctiva and retina.
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Drug Interactions
ACE inhibitors, α-blockers, amantadine, general anaesthetics, angiotensin-II receptor antagonists, antiarrhythmics, tricyclic antidepressants, anxiolytics and hypnotics, apomorphine, artemether with lumefantrine, barbiturates, bromocriptine, cabergoline, calcium-channel blockers, carbamazepine, cimetidine, ethosuximide, levodopa, lisuride, memantine, methyldopa, metoclopramide, opioid analgesics, oxcarbazepine, pergolide, phenytoin, pramipexole, primidone, ritonavir, ropinirole, sibutramine, sympathomimetics, terfenadine, tetrabenazine, tramadol, valproate.
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CIMS Class
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ATC Classification
N05AD06 - bromperidol ; Belongs to the class of butyrophenone derivatives antipsychotics.
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