Caspofungin


Generic Medicine Info
Contraindications
Hypersensitivity.
Special Precautions
Hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor hepatic function.
Adverse Reactions
Diarrhoea, nausea, vomiting, flushing, headache, fever, chills, arthralgia, phlebitis, tachycardia, rash, erythema, facial swelling, pruritus, hyperhidrosis, warm sensation, dyspnoea, bronchospasm; hyperhidrosis, hypokalaemia, increased liver enzymes and alkaline phosphatase, decreased RBC and WBC levels; pulmonary oedema, adult resp distress syndrome (ARDS), radiographic infiltrates (invasive aspergillosis).
Potentially Fatal: Anaphylaxis, severe toxic epidermal necrolysis, Stevens-Johnson syndrome.
Drug Interactions
Reduced plasma concentration w/ rifampicin and other CYP enzyme inducers. May increase hepatic enzymes w/ ciclosporin. May decrease blood concentration of tacrolimus.
CIMS Class
Antifungals
ATC Classification
J02AX04 - caspofungin ; Belongs to the class of other systemic antimycotics.
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