Delapril


Generic Medicine Info
Contraindications
Aortic stenosis or outflow tract obstruction, active or suspected renovascular disease. Pregnancy.
Special Precautions
Patient w/ history of idiopathic or hereditary angioedema, diarrhoea, water or Na depletion, peripheral vascular disease or generalised atherosclerosis, collagen vascular disorders (e.g. SLE, scleroderma). Renal impairment. Lactation. Monitoring Parameters Assessment of renal function prior and throughout therapy. Monitor serum K level, WBC count and presence of protein in urine regularly.
Adverse Reactions
Hypotension, dizziness, fatigue, headache, GI disturbances, persistent dry cough and other upper resp tract symptoms, angioedema, blood disorders (e.g. neutropenia and agranulocytosis), hyperkalaemia, hyponatraemia, skin rashes.
Drug Interactions
Additive hyperkalaemic effects w/ K-sparing diuretics, K supplements, other drugs that can cause hyperkalaemia (e.g. ciclosporin, indometacin).
ATC Classification
C09AA12 - delapril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.
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