Difemerine: Indication, Dosage, Side Effect, Precaution

Concise Prescribing Info Full Prescribing Info

Dosage/Direction for Use Contraindications Special Precautions Adverse Reactions Action CIMS Class ATC Classification

Concise Prescribing Info

Indications/Uses

Visceral spasms.

Dosage/Direction for Use

Adult: PO 7.5-10 mg/day.

Contraindications

Prostatic enlargement, paralytic ileus, pyloric stenosis, closed-angle glaucoma, myasthenia gravis.

Special Precautions

Childn and elderly; febrile conditions, tachycardia, acute MI, hypertension, ulcerative colitis, diarrhoea. May impair ability to drive or operate machinery. Pregnancy and lactation.

Adverse Reactions

Dryness of mouth, difficulty in swallowing and talking, thirst, reduced bronchial secretions, mydriasis with cycloplegia, photophobia, flushing, dryness of skin, transient bradycardia followed by tachycardia with palpitations and arrhythmias, difficulty in micturition, reduced tone and motility of GIT, vomiting.

CIMS Class

Antispasmodics

ATC Classification

A03AA09 - difemerine ; Belongs to the class of synthetic anticholinergics, esters with tertiary amino group. Used in the treatment of functional bowel disorders.

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