Glafenine


Concise Prescribing Info
Indications/Uses
Pain and inflammation.
Dosage/Direction for Use
Adult: PO 200-400 mg 3-4 times/day.
Contraindications
Peptic ulceration; hypersensitivity to NSAIDs/aspirin; moderate/severe renal impairment.
Special Precautions
Liver failure. Drink plenty of fluid to reduce the risk of crystallization in the urinary tract. To be discontinued at the 1st sign of allergic reaction. Patient with infection; haemorrhagic disorders; hypertension; cardiac function; asthma. Pregnancy and lactation.
Adverse Reactions
Anaphylaxis; hepatotoxicity; nephrotoxicity; GI disturbances; crystallization in the urinary tract; cross-reactivity with floctafenine.
Drug Interactions
Oral anticoagulants; antivirals; phenytoin; sulfonylurea antidiabetic; methotrexate; cardiac glycosides; ACE inhibitors; diuretics; β-blocker; other NSAIDs; lithium; ciclosporin; tacrolimus; moclobemide. Corticosteroids; antiplatelet drugs, biphosphonates, SSRIs and pentoxifylline increase GI bleeding risk. Avoid alcohol and tobacco.
ATC Classification
N02BG03 - glafenine ; Belongs to the class of other analgesics and antipyretics.
Disclaimer: This information is independently developed by CIMS based on glafenine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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