Mepacrine


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult: PO Giardiasis 100 mg 3 times/day for 5-7 days. Lupus erythematosus 100 mg once daily for the 1st 1-2 mth. Maintenance: 25-50 mg/day several times a wk. Intrapleural Prophylaxis of pneumothorax Instill 100 mg once daily for 3-4 consecutive days.
Contraindications
Hypersensitivity; psoriasis.
Special Precautions
Elderly, history of psychosis, hepatic disease, porphyria. Pregnancy and lactation.
Adverse Reactions
Dizziness, headache; nausea, vomiting; reversible yellow discolouration of the skin, conjunctiva, urine (on prolonged use); blue-black discolouration of the palate and nails; psychosis, CNS stimulation, convulsions; ocular toxicity chronic dermatoses; rarely, liver toxicity and aplastic anaemia.
Drug Interactions
May produce disulfiram-type reaction with alcohol. May increase plasma concentrations and toxicity of primaquine.
ATC Classification
P01AX05 - mepacrine ; Belongs to the class of other agents used in the treatment amoebiasis and other protozoal diseases.
Disclaimer: This information is independently developed by CIMS based on mepacrine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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